Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADU48323.1RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR013123: IPR001537: IPR004441; KEGG: ami:Amir_6302 RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA meth [...] (251 aa)    
Predicted Functional Partners:
ADU46594.1
KEGG: ami:Amir_0884 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.676
ADU46593.1
KEGG: ami:Amir_0885 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.666
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR002547: IPR005121: IPR004532: IPR005146: IPR 005147; KEGG: kra:Krad_3163 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding domain; B3/4 domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spiroch [...]
 
  
 0.593
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
 
 0.537
ADU48556.1
COGs: COG0557 Exoribonuclease R; InterPro IPR001900; KEGG: kse:Ksed_12120 exoribonuclease R; PFAM: ribonuclease II; SPTR: Putative ribonuclease R; PFAM: RNB domain.
  
 
 0.531
ADU48047.1
COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006224: IPR006145; KEGG: sen:SACE_3351 ribosomal pseudouridine synthase; PFAM: pseudouridine synthase; SPTR: Putative RNA pseudouridylate synthase; PFAM: RNA pseudouridylate synthase.
 
 
 0.510
rplT
LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
 
 
 0.507
ADU48321.1
NADPH-dependent FMN reductase; COGs: COG0431 flavoprotein; InterPro IPR005025; KEGG: gob:Gobs_2153 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; TIGRFAM: FMN reductase, MsuE subfamily.
       0.496
ADU48322.1
Luciferase-like, subgroup; COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR016048; KEGG: ske:Sked_18700 flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase; PFAM: Luciferase-like, subgroup; SPTR: Flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase; PFAM: Luciferase-like monooxygenase.
       0.496
ADU48319.1
COGs: COG0009 Putative translation factor (SUA5); InterPro IPR006070: IPR004388; KEGG: ami:Amir_4990 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: Putative uncharacterized protein; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family.
 
  
 0.481
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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