STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48329.1Protein of unknown function DUF151; COGs: COG1259 conserved hypothetical protein; InterPro IPR003729; KEGG: nca:Noca_2711 hypothetical protein; PFAM: protein of unknown function DUF151; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised ACR, COG1259. (164 aa)    
Predicted Functional Partners:
ADU48328.1
Regulatory protein MerR; InterPro IPR000551; KEGG: aau:AAur_1684 hypothetical protein; SMART: regulatory protein MerR; SPTR: Putative uncharacterized protein.
     
 0.862
ADU48330.1
Regulatory protein MerR; InterPro IPR000551; KEGG: nca:Noca_2712 regulatory protein, MerR; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: Putative uncharacterized protein; manually curated; PFAM: MerR family regulatory protein.
 
   
 0.762
ADU48333.1
Protein of unknown function DUF881; COGs: COG3879 conserved hypothetical protein; InterPro IPR010273; KEGG: xce:Xcel_1737 protein of unknown function DUF881; PFAM: protein of unknown function DUF881; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF881).
     
 0.689
ADU48331.1
COGs: COG1716 FOG: FHA domain; InterPro IPR000253; KEGG: kfl:Kfla_3173 FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: FHA domain.
     
 0.650
ADU48335.1
Protein of unknown function DUF881; COGs: COG3879 conserved hypothetical protein; InterPro IPR010273; KEGG: sco:SCO1387 membrane associated protein; PFAM: protein of unknown function DUF881; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF881).
     
 0.617
arc
AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
    0.596
gcvP
Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
       0.478
ADU48334.1
Protein of unknown function DUF1290; COGs: COG3856 conserved hypothetical protein (small basic protein); InterPro IPR009709; KEGG: ske:Sked_18240 uncharacterized conserved protein (small basic protein); PFAM: protein of unknown function DUF1290; SPTR: Putative membrane protein; PFAM: Protein of unknown function (DUF1290).
       0.446
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
       0.437
ADU48336.1
CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase; COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR000462: IPR004570; KEGG: sma:SAV_6976 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: Putative phosphatidylglycerophosphate synthase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.430
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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