Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADU48392.1COGs: COG3850 Signal transduction histidine kinase nitrate/nitrite-specific; InterPro IPR011712: IPR003594: IPR005467; KEGG: ttr:Tter_2549 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; SPTR: GAF sensor signal transduction histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (599 aa)    
Predicted Functional Partners:
ADU48393.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: tbi:Tbis_0775 LuxR family two component transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.954
ADU47488.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789: IPR000792; KEGG: kra:Krad_4263 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.808
ADU49830.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: lxx:Lxx07500 two-component system, regulatory protein; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: LuxR family DNA-binding response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.808
ADU49009.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: sro:Sros_1417 response regulator receiver protein; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.807
ADU49497.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789: IPR000792; KEGG: nca:Noca_2943 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.807
ADU49814.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: nca:Noca_0992 regulatory protein, LuxR; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Putative two-component system response transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.806
ADU47497.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789: IPR000792; KEGG: bcv:Bcav_3033 two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; response regulator receiver; SPTR: Putative two-component system DNA-binding response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family.
 
 
 0.805
ADU48478.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: sgr:SGR_5383 putative two-component system response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Putative two-component system response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.804
ADU47103.1
ATP-dependent transcriptional regulator, MalT-like, LuxR family; COGs: COG2909 ATP-dependent transcriptional regulator protein; InterPro IPR000792; KEGG: pna:Pnap_3341 response regulator receiver protein; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: Transcriptional regulator, LuxR family; PFAM: Bacterial regulatory proteins, luxR family.
 
 
 0.750
ADU49167.1
Transcriptional regulator, LuxR family; COGs: COG3899 ATPase; InterPro IPR000792; KEGG: vap:Vapar_3549 transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: Putative uncharacterized protein; PFAM: Archaeal ATPase; Bacterial regulatory proteins, luxR family.
 
 
 0.691
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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