STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
ADU48416.1methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: kfl:Kfla_3725 methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Methionine-R-sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family. (139 aa)    
Predicted Functional Partners:
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.994
ADU48415.1
KEGG: kra:Krad_1592 secreted protein; SPTR: Secreted protein.
       0.636
ADU49061.1
NAD(+) diphosphatase; COGs: COG2816 NTP pyrophosphohydrolase containing a Zn-finger probably nucleic-acid-binding; InterPro IPR015375: IPR015376: IPR000086: IPR020084; KEGG: tbi:Tbis_2968 NAD(+) diphosphatase; PFAM: NUDIX hydrolase; Zinc ribbon NADH pyrophosphatase; NADH pyrophosphatase-like; PRIAM: NAD(+) diphosphatase; SPTR: NADH pyrophosphatase; PFAM: NADH pyrophosphatase zinc ribbon domain; NUDIX domain; NADH pyrophosphatase-like rudimentary NUDIX domain.
 
      0.603
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
 
 0.589
ADU46822.1
NHL repeat containing protein; InterPro IPR000866: IPR001258: IPR017936; KEGG: ach:Achl_3716 NHL repeat containing protein; PFAM: NHL repeat containing protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: NHL repeat containing protein; PFAM: NHL repeat; AhpC/TSA family.
   
 0.568
ADU47210.1
Redoxin domain protein; InterPro IPR017909: IPR017936: IPR013740; KEGG: kse:Ksed_24350 thiol-disulfide isomerase-like thioredoxin; PFAM: Redoxin domain protein; SPTR: Putative uncharacterized protein; PFAM: Redoxin.
   
 0.568
ADU49888.1
Catalase; COGs: COG0753 Catalase; InterPro IPR018028: IPR010582: IPR011614: IPR002226; KEGG: sco:SCO0379 catalase; PFAM: Catalase related subgroup; Catalase domain protein; PRIAM: Catalase; SPTR: Catalase; PFAM: Catalase; Catalase-related immune-responsive; Belongs to the catalase family.
   
  
 0.553
rpmJ
LSU ribosomal protein L36P; InterPro IPR000473; KEGG: kse:Ksed_20630 50S ribosomal protein L36; PFAM: ribosomal protein L36; SPTR: 50S ribosomal protein L36; TIGRFAM: ribosomal protein L36; PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type; Belongs to the bacterial ribosomal protein bL36 family.
    
 
 0.477
ADU49201.1
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
   
  
 0.472
rplT
LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
 
 0.434
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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