STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48418.1Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (472 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.995
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
 
 0.994
ADU47337.1
Protoporphyrin IX magnesium-chelatase; COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR003593: IPR002035: IPR011704; KEGG: nml:Namu_0159 magnesium chelatase; PFAM: von Willebrand factor type A; ATPase associated with various cellular activities AAA_5; PRIAM: Magnesium chelatase; SMART: von Willebrand factor type A; AAA ATPase; SPTR: Magnesium chelatase; PFAM: Magnesium chelatase, subunit ChlI; von Willebrand factor type A domain.
  
 
 0.942
ADU48769.1
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
  
 
0.923
ADU49720.1
COGs: COG1239 Mg-chelatase subunit ChlI; KEGG: nca:Noca_0952 putative magnesium chelatase subunit ChlI; SPTR: Putative magnesium chelatase subunit ChlI.
   
 
 0.916
ADU48417.1
Chlorite dismutase; COGs: COG3253 conserved hypothetical protein; InterPro IPR010644; KEGG: kfl:Kfla_3727 chlorite dismutase; PFAM: Chlorite dismutase; SPTR: Putative uncharacterized protein; PFAM: Chlorite dismutase.
 
  
 0.894
ADU49011.1
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: gob:Gobs_4282 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; manually curated; PFAM: Phosphoribosyl transferase domain.
  
    0.733
ADU48419.1
KEGG: sgr:SGR_1471 hypothetical protein; SPTR: Putative lipoprotein.
     
 0.631
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
   
 0.627
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.566
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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