STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48427.1COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; InterPro IPR001387: IPR001986; KEGG: scb:SCAB_21131 putative UDP-N-acetylglucosamine transferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Putative UDP-N-acetylglucosamine transferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Helix-turn-helix; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase. (509 aa)    
Predicted Functional Partners:
murB
UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
 
  
 0.955
glmU
Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
  
 
 0.921
ADU49142.1
UDP-N-acetylglucosamine 4,6-dehydratase; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025: IPR003869; KEGG: kfl:Kfla_0497 polysaccharide biosynthesis protein CapD; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Polysaccharide biosynthesis protein CapD; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase.
    
 0.913
ADU49778.1
COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: krh:KRH_12670 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
  
 
  0.907
ADU49149.1
Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014026: IPR014027; KEGG: bbr:BB0876 polysaccharide biosynthesis protein; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Putative lipopolysaccharide biosynthesis protein; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose [...]
    
  0.906
ADU49773.1
Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterProIPR016160: IPR017476: IPR001732: IPR014026: IPR 014027; KEGG: kse:Ksed_26760 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrog [...]
    
  0.906
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
     
 
0.900
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.713
ADU48426.1
COGs: COG0702 nucleoside-diphosphate-sugar epimerase; KEGG: rha:RHA1_ro08384 nucleoside diphosphate sugar epimerase; SPTR: Possible nucleoside diphosphate sugar epimerase; PFAM: NmrA-like family.
       0.693
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
  
  
 0.663
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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