STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU48427.1COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; InterPro IPR001387: IPR001986; KEGG: scb:SCAB_21131 putative UDP-N-acetylglucosamine transferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Putative UDP-N-acetylglucosamine transferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Helix-turn-helix; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase. (509 aa)    
Predicted Functional Partners:
murB
UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
 
  
 0.952
glmU
Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
    
 0.923
ADU49778.1
COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: krh:KRH_12670 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
  
 
 0.908
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
     
 
0.900
ADU47418.1
Molybdenum cofactor synthesis domain protein; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterProIPR002618: IPR005110: IPR001453: IPR005111: IPR 020817; KEGG: kfl:Kfla_5768 UTP--glucose-1-phosphate uridylyltransferase; PFAM: UTP--glucose-1-phosphate uridylyltransferase; MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; PRIAM: UTP--glucose-1-phosphate uridylyltransferase; SPTR: UTP--glucose-1-phosphate uridylyltransferase; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-termi [...]
    
 0.818
ADU47692.1
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
    
 0.818
ADU47724.1
COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835: IPR001538; KEGG: nca:Noca_1407 mannose-1-phosphate guanylyltransferase (GDP); PFAM: Nucleotidyl transferase; mannose-6-phosphate isomerase type II; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase.
    
  0.814
ADU48426.1
COGs: COG0702 nucleoside-diphosphate-sugar epimerase; KEGG: rha:RHA1_ro08384 nucleoside diphosphate sugar epimerase; SPTR: Possible nucleoside diphosphate sugar epimerase; PFAM: NmrA-like family.
       0.692
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.585
ADU46986.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...]
     
 0.583
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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