STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48429.1Putative transcriptional regulator, PucR family; COGs: COG2508 Regulator of polyketide synthase expression; InterPro IPR003018; KEGG: kfl:Kfla_5320 putative phytochrome sensor protein; PFAM: GAF domain protein; SMART: GAF domain protein; SPTR: GAF domain protein; PFAM: GAF domain. (623 aa)    
Predicted Functional Partners:
ADU48428.1
COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198: IPR011294: IPR020904; KEGG: kfl:Kfla_5322 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: 3-hydroxybutyrate dehydrogenase; TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short chain dehydrogenase; TIGRFAM: 3-hydroxybutyrate dehydrogenase.
 
     0.843
ADU49743.1
PTS system D-fructose-specific IIABC components (F1P-forming), Frc family; COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR002178: IPR013011: IPR013014: IPR004715: IPR 003353: IPR006327: IPR003352; KEGG: sco:SCO3196 fructose-specific permease; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: Fructose-specific permease; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: Phosphotransferase s [...]
      
 0.699
ADU46986.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...]
  
 
 0.602
ADU47441.1
Peptidase M36 fungalysin; InterPro IPR000421: IPR001842; KEGG: rxy:Rxyl_2538 coagulation factor 5/8 type-like protein; PFAM: peptidase M36 fungalysin; coagulation factor 5/8 type domain protein; SPTR: Coagulation factor 5/8 type-like protein; PFAM: F5/8 type C domain; Fungalysin/Thermolysin Propeptide Motif; Fungalysin metallopeptidase (M36).
  
     0.574
ADU49742.1
COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR001020: IPR000032: IPR005698; KEGG: cmi:CMM_1505 phosphotransferase system, phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; SPTR: Phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
    
 
 0.480
ADU46704.1
Transcriptional regulator, LuxR family; COGs: COG3899 ATPase; InterPro IPR000792; KEGG: nca:Noca_4382 regulatory protein, LuxR; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: Putative LuxR-family transcriptional regulator; PFAM: Bacterial regulatory proteins, luxR family.
 
 
 0.474
ADU47793.1
InterPro IPR002477; KEGG: sna:Snas_2804 peptidoglycan-binding domain 1 protein; PFAM: Peptidoglycan-binding domain 1 protein; SPTR: Putative uncharacterized protein; PFAM: Putative peptidoglycan binding domain.
  
     0.469
ADU48427.1
COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; InterPro IPR001387: IPR001986; KEGG: scb:SCAB_21131 putative UDP-N-acetylglucosamine transferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Putative UDP-N-acetylglucosamine transferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Helix-turn-helix; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase.
  
    0.457
ADU49390.1
KEGG: pjd:Pjdr2_2870 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.445
ADU49764.1
COGs: COG3629 DNA-binding transcriptional activator of the SARP family; InterProIPR019775: IPR019782: IPR017986: IPR001680: IPR 001867: IPR005158; KEGG: nml:Namu_2911 transcriptional regulator, SARP family; PFAM: transcriptional activator domain; transcriptional regulator domain-containing protein; SPTR: Transcriptional regulator, SARP family; PFAM: Bacterial transcriptional activator domain; Transcriptional regulatory protein, C terminal.
 
    0.438
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.