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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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ADU48440.1Amino acid/polyamine/organocation transporter, APC superfamily; COGs: COG0531 Amino acid transporter; KEGG: cfl:Cfla_1709 hypothetical protein; SPTR: Probable membrane protein; TC 2.A.3. (673 aa)    
Predicted Functional Partners:
ADU48441.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR006036: IPR003148: IPR006037; KEGG: kfl:Kfla_3761 TrkA-N domain protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: Potassium uptake protein; manually curated; PFAM: TrkA-N domain; TrkA-C domain.
 
   
 0.854
ADU48442.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR006036: IPR003148: IPR006037; KEGG: ske:Sked_16160 K+ transport system, NAD-binding component; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: Putative potassium uptake protein; PFAM: TrkA-N domain; TrkA-C domain.
 
   
 0.821
ADU48439.1
23S rRNA m(5)U-1939 methyltransferase; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR002792; KEGG: kra:Krad_1564 deoxyribonuclease/rho motif-related TRAM; PFAM: deoxyribonuclease/rho motif-related TRAM; SPTR: Putative RNA methyltransferase; PFAM: tRNA (Uracil-5-)-methyltransferase; TRAM domain; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
       0.800
ADU48444.1
KEGG: tcu:Tcur_1708 nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Nucleic acid binding OB-fold tRNA/helicase-type.
 
     0.729
ADU48438.1
Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
   
 
 0.628
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
  
 0.501
ADU49215.1
Alpha-1,6-glucosidase, pullulanase-type; COGs: COG1523 Type II secretory pathway pullulanase PulA and related glycosidase; InterPro IPR006589: IPR011839: IPR006047: IPR004193; KEGG: kfl:Kfla_2775 alpha-1,6-glucosidase, pullulanase-type; PFAM: alpha amylase catalytic region; glycoside hydrolase family 13 domain protein; SMART: alpha amylase catalytic sub domain; SPTR: Alpha-1,6-glucosidase, pullulanase-type; TIGRFAM: alpha-1,6-glucosidase, pullulanase-type; PFAM: Domain of unknown function (DUF3372); Alpha amylase, catalytic domain; Carbohydrate-binding module 48 (Isoamylase N-terminal [...]
  
 0.469
ADU46998.1
Alpha amylase catalytic region; COGs: COG0366 Glycosidase; InterPro IPR006047: IPR006589; KEGG: mrd:Mrad2831_0315 alpha amylase catalytic region; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Alpha amylase catalytic region; PFAM: Alpha amylase, catalytic domain; TIGRFAM: trehalose synthase.
   
 0.459
ADU47002.1
Alpha amylase catalytic region; COGs: COG0366 Glycosidase; InterPro IPR006047: IPR006589; KEGG: mgi:Mflv_3723 alpha amylase, catalytic region; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Alpha amylase, catalytic region; PFAM: Alpha amylase, catalytic domain; TIGRFAM: trehalose synthase.
   
 0.459
ADU47873.1
Alpha amylase catalytic region; COGs: COG0366 Glycosidase; InterPro IPR006047: IPR006589; KEGG: cfl:Cfla_2176 alpha amylase catalytic region; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Putative alpha-glucosidase; PFAM: Alpha amylase, catalytic domain.
   
 0.459
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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