STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48444.1KEGG: tcu:Tcur_1708 nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Nucleic acid binding OB-fold tRNA/helicase-type. (133 aa)    
Predicted Functional Partners:
ADU48443.1
KEGG: kse:Ksed_15770 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3159).
       0.837
ADU48445.1
KEGG: kra:Krad_1558 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3710).
       0.766
ADU48440.1
Amino acid/polyamine/organocation transporter, APC superfamily; COGs: COG0531 Amino acid transporter; KEGG: cfl:Cfla_1709 hypothetical protein; SPTR: Probable membrane protein; TC 2.A.3.
 
     0.729
ADU48442.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR006036: IPR003148: IPR006037; KEGG: ske:Sked_16160 K+ transport system, NAD-binding component; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: Putative potassium uptake protein; PFAM: TrkA-N domain; TrkA-C domain.
  
     0.671
ADU48447.1
KEGG: bcv:Bcav_1935 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.641
ADU48441.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR006036: IPR003148: IPR006037; KEGG: kfl:Kfla_3761 TrkA-N domain protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: Potassium uptake protein; manually curated; PFAM: TrkA-N domain; TrkA-C domain.
  
     0.632
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
     
 0.605
ADU48485.1
Cyclase/dehydrase; InterPro IPR005031; KEGG: amd:AMED_2448 cyclase/dehydrase; PFAM: cyclase/dehydrase; SPTR: Putative uncharacterized protein; PFAM: Polyketide cyclase / dehydrase and lipid transport.
  
     0.572
ADU47173.1
KEGG: bcv:Bcav_0722 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Lsr2.
  
     0.544
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.536
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.