STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (359 aa)    
Predicted Functional Partners:
ADU48418.1
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
 
 
 0.994
ADU48769.1
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
 
 
 0.993
ADU48417.1
Chlorite dismutase; COGs: COG3253 conserved hypothetical protein; InterPro IPR010644; KEGG: kfl:Kfla_3727 chlorite dismutase; PFAM: Chlorite dismutase; SPTR: Putative uncharacterized protein; PFAM: Chlorite dismutase.
  
 0.980
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.974
ADU47337.1
Protoporphyrin IX magnesium-chelatase; COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR003593: IPR002035: IPR011704; KEGG: nml:Namu_0159 magnesium chelatase; PFAM: von Willebrand factor type A; ATPase associated with various cellular activities AAA_5; PRIAM: Magnesium chelatase; SMART: von Willebrand factor type A; AAA ATPase; SPTR: Magnesium chelatase; PFAM: Magnesium chelatase, subunit ChlI; von Willebrand factor type A domain.
  
 
 0.938
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
   
 
 0.920
ADU49784.1
Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
     
 0.917
ADU48770.1
Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR017200: IPR007197; KEGG: nca:Noca_4381 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily.
  
 
 0.915
ADU49335.1
Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR006638: IPR017200: IPR007197; KEGG: nca:Noca_1430 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily.
  
 
 0.915
ADU49489.1
COGs: COG2132 Putative multicopper oxidase; InterProIPR017909: IPR011707: IPR001117: IPR011706: IPR 002355; KEGG: pfr:PFREUD_19350 multicopper oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 1; multicopper oxidase type 2; SPTR: Multicopper oxidase; PFAM: Multicopper oxidase; TIGRFAM: copper-resistance protein, CopA family.
   
 
 0.914
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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