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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48454.1Type I phosphodiesterase/nucleotide pyrophosphatase; COGs: COG1524 Uncharacterized protein of the AP superfamily; InterPro IPR002591; KEGG: kra:Krad_1550 type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: Putative uncharacterized protein; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase. (385 aa)    
Predicted Functional Partners:
ADU48453.1
COGs: COG1435 Thymidine kinase; InterPro IPR001267: IPR020634; KEGG: kse:Ksed_15850 thymidine kinase; PFAM: thymidine kinase; PRIAM: Thymidine kinase; SPTR: Thymidine kinase; PFAM: Thymidine kinase.
  
    0.829
ADU48455.1
KEGG: kse:Ksed_15870 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.766
ADU48456.1
CoA-binding domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR000182: IPR003781; KEGG: kra:Krad_1548 CoA-binding domain protein; PFAM: CoA-binding domain protein; GCN5-related N-acetyltransferase; SPTR: Putative uncharacterized protein; PFAM: CoA binding domain; Acetyltransferase (GNAT) family.
 
     0.628
ADU48361.1
InterPro IPR007139; KEGG: kra:Krad_3046 protein of unknown function DUF349; PFAM: protein of unknown function DUF349; SPTR: Putative uncharacterized protein; manually curated; PFAM: Domain of Unknown Function (DUF349).
  
     0.562
ADU48537.1
KEGG: kra:Krad_3289 integral membrane protein; SPTR: Integral membrane protein.
  
     0.553
ADU48458.1
COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205: IPR006691; KEGG: kfl:Kfla_3453 DNA topoisomerase (ATP-hydrolyzing); PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: DNA gyrase subunit A; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal domain, beta-propeller.
 
     0.515
atpE
ATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
  
  0.430
ADU48445.1
KEGG: kra:Krad_1558 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3710).
  
     0.419
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.417
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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