Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADU48457.1COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: gob:Gobs_3234 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family. (208 aa)    
Predicted Functional Partners:
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
  
  
 0.683
cobB
Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
  
 0.633
ADU48268.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.612
ADU48458.1
COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205: IPR006691; KEGG: kfl:Kfla_3453 DNA topoisomerase (ATP-hydrolyzing); PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: DNA gyrase subunit A; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal domain, beta-propeller.
     
 0.612
ADU47165.1
ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR000412: IPR013525; KEGG: nca:Noca_0479 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: Putative ABC transporter permease protein; PFAM: ABC-2 type transporter; TIGRFAM: ABC transporter efflux protein, DrrB family.
  
  
 0.599
ADU48212.1
ABC-2 type transporter; InterPro IPR013525; KEGG: kse:Ksed_13310 ABC-type multidrug transport system, permease component; PFAM: ABC-2 type transporter; SPTR: ABC-type multidrug transport system, permease component; PFAM: ABC-2 type transporter; TIGRFAM: ABC transporter efflux protein, DrrB family.
  
  
 0.599
ADU49713.1
ABC-2 type transporter; InterPro IPR000412: IPR013526: IPR013525; KEGG: kse:Ksed_25220 ABC-type polysaccharide/polyol phosphate export systems, permease component; PFAM: ABC-2 type transporter; SPTR: ABC-type polysaccharide/polyol phosphate export systems, permease component; PFAM: ABC-2 type transporter; TIGRFAM: ABC-2 type transporter, NodJ family.
  
  
 0.599
ADU49855.1
ABC-2 type transporter; InterPro IPR013525; KEGG: saq:Sare_4005 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter; PFAM: ABC-2 type transporter.
  
  
 0.599
ADU49933.1
ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525: IPR000412; KEGG: mjl:Mjls_4638 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter; manually curated; PFAM: ABC-2 type transporter.
  
  
 0.599
ADU50071.1
ABC-2 type transporter; InterPro IPR013525: IPR000412; KEGG: kra:Krad_2016 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter; PFAM: ABC-2 type transporter; TIGRFAM: ABC transporter efflux protein, DrrB family.
  
  
 0.599
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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