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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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ADU48473.1Lytic transglycosylase catalytic; InterPro IPR018392: IPR008258: IPR002482; KEGG: ach:Achl_1556 lytic transglycosylase catalytic; PFAM: Lytic transglycosylase catalytic; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Lytic transglycosylase catalytic; PFAM: Transglycosylase SLT domain; LysM domain. (321 aa)    
Predicted Functional Partners:
ADU48474.1
COGs: COG0515 Serine/threonine protein kinase; InterProIPR017442: IPR005543: IPR020635: IPR002290: IPR 008271: IPR000719; KEGG: nca:Noca_3086 protein kinase; PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein; SPTR: Serine/threonine kinase; PFAM: Protein kinase domain; PASTA domain.
 
     0.684
ADU48475.1
Protein of unknown function DUF6 transmembrane; COGs: COG5006 permease DMT superfamily protein; InterPro IPR000620; KEGG: nca:Noca_3091 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Putative uncharacterized protein; PFAM: EamA-like transporter family.
       0.581
ADU48472.1
KEGG: kra:Krad_3230 hypothetical protein; SPTR: Putative transcriptional regulatory protein; TIGRFAM: DNA binding domain, excisionase family.
 
     0.545
ADU49062.1
COGs: COG3173 aminoglycoside phosphotransferase; InterPro IPR002575; KEGG: kra:Krad_1175 aminoglycoside phosphotransferase; PFAM: aminoglycoside phosphotransferase; SPTR: Macrolide 2'-phosphotransferase; PFAM: Phosphotransferase enzyme family.
  
     0.527
ADU48452.1
KEGG: kra:Krad_1551 DNA-binding protein; SPTR: Putative DNA-binding protein; PFAM: Protein of unknown function (DUF3071).
  
  
 0.525
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
    0.506
ADU50112.1
Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002477: IPR002508; KEGG: kfl:Kfla_7065 cell wall hydrolase/autolysin; PFAM: cell wall hydrolase/autolysin; Peptidoglycan-binding domain 1 protein; SMART: cell wall hydrolase/autolysin; SPTR: Cell wall hydrolase/autolysin; PFAM: Putative peptidoglycan binding domain; N-acetylmuramoyl-L-alanine amidase.
  
  
 0.486
ADU49005.1
InterPro IPR018392; KEGG: cfl:Cfla_2323 peptidoglycan-binding lysin domain protein; PFAM: Peptidoglycan-binding lysin domain; SPTR: Putative uncharacterized protein; PFAM: LysM domain.
 
   
 0.458
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.448
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.434
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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