STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48478.1Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: sgr:SGR_5383 putative two-component system response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Putative two-component system response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (238 aa)    
Predicted Functional Partners:
ADU48479.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594; KEGG: cai:Caci_6058 putative signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: Putative signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
   0.920
ADU49498.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594: IPR005467: IPR013767: IPR011712; KEGG: nca:Noca_2942 ATPase domain-containing protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: ATP-binding region, ATPase domain protein domain protein; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.857
ADU49829.1
COGs: COG4585 Signal transduction histidine kinase; InterProIPR005467: IPR004358: IPR003594: IPR017205: IPR 011712; KEGG: sco:SCO1369 two component system histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; SPTR: Probable two component system histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.845
ADU48392.1
COGs: COG3850 Signal transduction histidine kinase nitrate/nitrite-specific; InterPro IPR011712: IPR003594: IPR005467; KEGG: ttr:Tter_2549 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; SPTR: GAF sensor signal transduction histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.813
ADU48480.1
COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: fre:Franean1_1829 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: Putative uncharacterized protein; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases.
       0.773
ADU49815.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003018: IPR011712: IPR003594; KEGG: saq:Sare_1529 GAF sensor signal transduction histidine kinase; PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; SPTR: GAF sensor signal transduction histidine kinase; PFAM: Histidine kinase; GAF domain.
 
 
 0.659
ADU48481.1
Hypothetical protein; InterPro IPR002202; KEGG: scb:SCAB_67571 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.551
ADU47489.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712: IPR003594; KEGG: pak:HMPREF0675_3336 histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SPTR: Putative two-component sensor kinase; PFAM: Histidine kinase.
 
 
 0.535
ADU48476.1
COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: nca:Noca_3094 L-threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Threonine aldolase; SPTR: L-allo-threonine aldolase; PFAM: Beta-eliminating lyase.
       0.531
ADU48477.1
COGs: COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002480; KEGG: kra:Krad_3233 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase class II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 2-dehydro-3-deoxyphosphoheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: Class-II DAHP synthetase family; TIGRFAM: 3-deoxy-7-phosphoheptulonate synthase, class II.
       0.531
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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