STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48479.1COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594; KEGG: cai:Caci_6058 putative signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: Putative signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (401 aa)    
Predicted Functional Partners:
ADU48478.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: sgr:SGR_5383 putative two-component system response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Putative two-component system response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
   0.920
ADU48480.1
COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: fre:Franean1_1829 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: Putative uncharacterized protein; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases.
       0.794
ADU48487.1
KEGG: kfl:Kfla_2801 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.643
ADU48477.1
COGs: COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002480; KEGG: kra:Krad_3233 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase class II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 2-dehydro-3-deoxyphosphoheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: Class-II DAHP synthetase family; TIGRFAM: 3-deoxy-7-phosphoheptulonate synthase, class II.
       0.636
ADU48476.1
COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: nca:Noca_3094 L-threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Threonine aldolase; SPTR: L-allo-threonine aldolase; PFAM: Beta-eliminating lyase.
       0.576
ADU48481.1
Hypothetical protein; InterPro IPR002202; KEGG: scb:SCAB_67571 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.565
ADU48203.1
COGs: COG3429 Glucose-6-P dehydrogenase subunit; InterPro IPR019297; KEGG: kra:Krad_2925 OpcA protein; PFAM: Glucose-6-phosphate dehydrogenase subunit; SPTR: OpcA protein; PFAM: Glucose-6-phosphate dehydrogenase subunit; TIGRFAM: opcA protein.
  
     0.529
ADU46986.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...]
  
 
 0.472
ADU48405.1
Hypothetical protein; InterPro IPR013434; KEGG: kfl:Kfla_3574 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Putative transmembrane protein (PGPGW); TIGRFAM: conserved hypothetical protein TIGR02611.
  
     0.465
ADU48452.1
KEGG: kra:Krad_1551 DNA-binding protein; SPTR: Putative DNA-binding protein; PFAM: Protein of unknown function (DUF3071).
  
     0.458
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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