STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ADU48499.1Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (592 aa)    
Predicted Functional Partners:
ADU48493.1
Cytochrome-c oxidase; COGs: COG1845 Heme/copper-type cytochrome/quinol oxidase subunit 3; InterPro IPR000298; KEGG: kse:Ksed_16180 heme/copper-type cytochrome/quinol oxidase, subunit 3; PFAM: cytochrome c oxidase subunit III; PRIAM: Cytochrome-c oxidase; SPTR: Heme/copper-type cytochrome/quinol oxidase, subunit 3; manually curated; PFAM: Cytochrome c oxidase subunit III.
 
 0.999
ADU48494.1
Menaquinol-cytochrome c reductase cytochrome c1 subunit precursor; InterPro IPR003088: IPR009152: IPR009056; KEGG: kse:Ksed_16190 cytochrome c, mono- and diheme variants family; PFAM: cytochrome c class I; SPTR: Cytochrome C heme-binding subunit; PFAM: Cytochrome c.
 
 
 0.999
ADU48498.1
Hypothetical protein; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
 
 0.999
ADU48500.1
COGs: COG1622 Heme/copper-type cytochrome/quinol oxidase subunit 2; InterPro IPR002429: IPR014222: IPR001505; KEGG: cfl:Cfla_2082 cytochrome c oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; SPTR: Cytochrome c oxidase subunit 2; TIGRFAM: cytochrome c oxidase, subunit II; PFAM: Cytochrome C oxidase subunit II, periplasmic domain; TIGRFAM: cytochrome c oxidase, subunit II.
 
 0.999
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 0.998
ADU48495.1
Menaquinol-cytochrome c reductase iron-sulfur subunit precursor; COGs: COG0723 Rieske Fe-S protein; InterPro IPR017941; KEGG: kse:Ksed_16200 Rieske Fe-S protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Rieske iron-sulphur component of ubiQ-cytB reductase; PFAM: Rieske [2Fe-2S] domain.
 
 
 0.998
ADU48496.1
COGs: COG1290 Cytochrome b subunit of the bc complex; InterPro IPR005797; KEGG: kse:Ksed_16210 cytochrome b subunit of the bc complex; PFAM: Cytochrome b/b6 domain; SPTR: Cytochrome B subunit; PFAM: Cytochrome b(N-terminal)/b6/petB.
 
 0.998
ADU49495.1
Cytochrome b/b6 domain; COGs: COG1290 Cytochrome b subunit of the bc complex; InterPro IPR005797: IPR019794; KEGG: nca:Noca_2944 cytochrome b/b6 domain-containing protein; PFAM: Cytochrome b/b6 domain; SPTR: Cytochrome b/b6, N-terminal domain; PFAM: Cytochrome b(N-terminal)/b6/petB.
 
 
 0.997
ADU46997.1
FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR017941: IPR006076; KEGG: nda:Ndas_1353 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; Rieske [2Fe-2S] iron-sulphur domain; SPTR: FAD dependent oxidoreductase; PFAM: Rieske [2Fe-2S] domain; FAD dependent oxidoreductase.
  
 
 0.940
ADU47242.1
COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR003918: IPR001750: IPR010227; KEGG: cfl:Cfla_2704 proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: NADH dehydrogenase subunit M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M.
  
 
 0.937
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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