Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU48527.1KEGG: cfl:Cfla_2099 hypothetical protein; SPTR: Putative uncharacterized protein. (115 aa)    
Predicted Functional Partners:
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.830
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 0.830
ADU47191.1
COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: kra:Krad_0611 histone deacetylase superfamily; PFAM: histone deacetylase superfamily; PRIAM: Histone deacetylase; SPTR: Putative acetoin utilization protein; PFAM: Histone deacetylase domain.
    
  0.810
ADU48211.1
KEGG: sro:Sros_6098 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 
 0.799
ADU49270.1
KEGG: kfl:Kfla_6144 hypothetical protein; SPTR: Putative uncharacterized protein.
    
 0.779
ADU49271.1
KEGG: sma:SAV_5893 hypothetical protein; SPTR: Putative uncharacterized protein.
    
 0.779
ADU49895.1
Ankyrin; InterPro IPR002110: IPR020683; KEGG: nda:Ndas_2707 ankyrin; PFAM: Ankyrin; SMART: Ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat.
    
 0.779
rpsG
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
    
   0.757
dnaJ
Chaperone DnaJ domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...]
    
  0.755
ADU49459.1
KEGG: sro:Sros_7035 hypothetical protein; SPTR: Putative uncharacterized protein.
    
  0.755
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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