STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48530.1Domain of unknown function DUF1731; COGs: COG1090 nucleoside-diphosphate sugar epimerase; InterPro IPR001509: IPR013549: IPR010099; KEGG: bcv:Bcav_1861 domain of unknown function DUF1731; PFAM: domain of unknown function DUF1731; NAD-dependent epimerase/dehydratase; SPTR: Putative NAD dependent epimerase/dehydratase family protein; PFAM: NAD dependent epimerase/dehydratase family; Domain of unknown function (DUF1731); TIGRFAM: conserved hypothetical protein TIGR01777. (301 aa)    
Predicted Functional Partners:
ADU48529.1
COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR000089: IPR004167: IPR001078: IPR014276: IPR 003016; KEGG: bcv:Bcav_1862 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain-containing protein of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; SPTR: Dihydrolipoamide acetyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: 2-oxoacid [...]
  
    0.834
ADU46707.1
TspO/MBR family protein; COGs: COG0702 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509: IPR004307; KEGG: krh:KRH_21230 hypothetical protein; PFAM: TspO/MBR family protein; NAD-dependent epimerase/dehydratase; SPTR: Putative uncharacterized protein; PFAM: TspO/MBR family; NmrA-like family.
 
    0.776
ADU48528.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR000815: IPR004099: IPR006258: IPR 012999; KEGG: kra:Krad_3278 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
  
    0.688
ADU48527.1
KEGG: cfl:Cfla_2099 hypothetical protein; SPTR: Putative uncharacterized protein.
     
 0.573
ADU48999.1
KEGG: sro:Sros_2595 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.559
ADU47817.1
InterPro IPR018702; KEGG: bcv:Bcav_2765 hypothetical protein; PFAM: Protein of unknown function DUF2207, membrane; SPTR: Putative uncharacterized protein; PFAM: Predicted membrane protein (DUF2207).
   
    0.500
ADU47299.1
Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001808: IPR001367: IPR007167; KEGG: kse:Ksed_24030 Mn-dependent transcriptional regulator; PFAM: iron dependent repressor; FeoA family protein; SMART: iron dependent repressor; regulatory protein Crp; SPTR: Iron-dependent repressor, DxtR metalloregulatory family protein; PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain.
   
    0.482
ADU48766.1
KEGG: cmi:CMM_1413 hypothetical protein; SPTR: Putative uncharacterized protein.
   
    0.482
ADU49426.1
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
   
    0.462
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
    0.435
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (16%) [HD]