Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ADU48532.1Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: ske:Sked_15440 predicted dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Putative oxidoreductase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain. (357 aa)    
Predicted Functional Partners:
lipB
Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
       0.567
ADU49310.1
Galactokinase; COGs: COG0153 Galactokinase; InterProIPR006206: IPR000705: IPR019539: IPR006204: IPR 013750: IPR019741: IPR006203; KEGG: cfl:Cfla_2490 galactokinase; PFAM: Galactokinase galactose-binding domain; GHMP kinase; GHMP kinase domain protein; SPTR: Galactokinase; TIGRFAM: galactokinase; PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; Belongs to the GHMP kinase family. GalK subfamily.
 
 
 0.553
ADU48531.1
COGs: COG0515 Serine/threonine protein kinase; InterProIPR017442: IPR020635: IPR002290: IPR017441: IPR 020929: IPR000719; KEGG: gob:Gobs_3363 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: Probable serine/threonine-protein kinase transcriptional regulatoryprotein pknk (Protein kinase k) (Stpk k); PFAM: Protein kinase domain.
  
    0.520
ADU48535.1
KEGG: ske:Sked_02620 hypothetical protein; SPTR: Putative uncharacterized protein.
 
    0.500
ADU48534.1
ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: kfl:Kfla_1062 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter.
       0.412
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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