STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48537.1KEGG: kra:Krad_3289 integral membrane protein; SPTR: Integral membrane protein. (247 aa)    
Predicted Functional Partners:
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
       0.798
ADU48515.1
KEGG: bcv:Bcav_1880 putative integral membrane protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3043).
 
     0.796
ADU48328.1
Regulatory protein MerR; InterPro IPR000551; KEGG: aau:AAur_1684 hypothetical protein; SMART: regulatory protein MerR; SPTR: Putative uncharacterized protein.
  
     0.766
ADU48445.1
KEGG: kra:Krad_1558 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3710).
  
     0.763
rbpA-2
Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
  
     0.755
ADU48447.1
KEGG: bcv:Bcav_1935 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.754
ADU48361.1
InterPro IPR007139; KEGG: kra:Krad_3046 protein of unknown function DUF349; PFAM: protein of unknown function DUF349; SPTR: Putative uncharacterized protein; manually curated; PFAM: Domain of Unknown Function (DUF349).
  
     0.747
ADU48422.1
KEGG: bcv:Bcav_1965 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3000).
  
     0.716
ADU48535.1
KEGG: ske:Sked_02620 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.677
glnE
(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]
  
     0.668
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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