STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48572.1Transcriptional regulator, CdaR family; COGs: COG2508 Regulator of polyketide synthase expression; KEGG: sco:SCO2386 hypothetical protein; SPTR: Putative uncharacterized protein. (414 aa)    
Predicted Functional Partners:
ADU48573.1
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043; KEGG: ach:Achl_2205 putative (acyl-carrier-protein) S-malonyltransferase; PFAM: Acyl transferase; PRIAM: [Acyl-carrier-protein] S-malonyltransferase; SPTR: Acyl-carrier-protein S-malonyltransferase; PFAM: Acyl transferase domain.
 
   
 0.884
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
     0.763
acpP
Phosphopantetheine-binding protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
     
 0.674
ADU49296.1
MaoC domain protein dehydratase; COGs: COG2030 Acyl dehydratase; InterPro IPR002539; KEGG: sco:SCO4637 hypothetical protein; PFAM: MaoC domain protein dehydratase; SPTR: Putative uncharacterized protein; PFAM: MaoC like domain.
  
     0.573
ADU49297.1
Hypothetical protein; InterPro IPR016709; KEGG: aau:AAur_3002 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: MaoC like domain; Belongs to the UPF0336 family.
  
     0.499
ADU48570.1
2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
       0.497
ADU48576.1
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
       0.476
argG
COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518: IPR018223; KEGG: nca:Noca_2474 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; manually curated; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
       0.468
ADU48203.1
COGs: COG3429 Glucose-6-P dehydrogenase subunit; InterPro IPR019297; KEGG: kra:Krad_2925 OpcA protein; PFAM: Glucose-6-phosphate dehydrogenase subunit; SPTR: OpcA protein; PFAM: Glucose-6-phosphate dehydrogenase subunit; TIGRFAM: opcA protein.
  
     0.416
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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