STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48582.1Transcriptional regulator, ArsR family; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001845: IPR001763; KEGG: rha:RHA1_ro11220 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; Rhodanese domain protein; SMART: regulatory protein ArsR; Rhodanese domain protein; SPTR: Possible transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family; Rhodanese-like domain. (219 aa)    
Predicted Functional Partners:
ADU48583.1
Major facilitator superfamily MFS_1; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701: IPR005829; KEGG: mva:Mvan_5862 major facilitator superfamily transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily.
 
  
 0.948
ADU47307.1
Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121: IPR001757: IPR008250: IPR005834: IPR 006403: IPR006416: IPR018303; KEGG: rha:RHA1_ro11210 copper-exporting ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Putative cation-transporting ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy-metal-associated doma [...]
  
  
 0.754
ADU49484.1
Copper-translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR011017: IPR001757: IPR000695: IPR008250: IPR 005834: IPR007029: IPR006403: IPR006416: IPR018303; KEGG: nca:Noca_2922 copper-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; YHS domain-containing protein; SMART: TRASH domain-containing protein; SPTR: Copper-translocating P-type ATPase; TIGRFAM: copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC [...]
  
  
 0.639
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
  
  
 0.625
ADU49537.1
DsrE family protein; COGs: COG1553 conserved hypothetical protein involved in intracellular sulfur reduction; InterPro IPR003787; KEGG: rfr:Rfer_0463 DsrE-like protein; PFAM: DsrE family protein; SPTR: DsrE-like protein; PFAM: DsrE/DsrF-like family.
 
  
 0.596
ADU47946.1
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: gob:Gobs_0866 silent information regulator protein Sir2; PFAM: Silent information regulator protein Sir2; SPTR: Putative SIR2-like regulatory protein; PFAM: Sir2 family.
  
    0.574
ADU48581.1
Rieske (2Fe-2S) iron-sulfur domain; COGs: COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase; InterPro IPR017941; KEGG: mlu:Mlut_20070 nitrite reductase (NAD(P)H), small subunit; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Rieske (2Fe-2S) domain protein; PFAM: Rieske [2Fe-2S] domain.
  
    0.559
ADU49337.1
InterPro IPR013096; KEGG: pfr:PFREUD_02140 hypothetical protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Putative uncharacterized protein; PFAM: Cupin domain.
  
    0.539
ADU49967.1
InterPro IPR004360; KEGG: kfl:Kfla_4696 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase/bleomycin resistance protein/dioxygenase; manually curated; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.
  
    0.529
ADU47824.1
Protein of unknown function DUF179; COGs: COG1678 Putative transcriptional regulator protein; InterPro IPR003774; KEGG: kra:Krad_3774 hypothetical protein; PFAM: protein of unknown function DUF179; SPTR: UPF0301 protein Krad_3774; PFAM: Uncharacterized ACR, COG1678.
  
    0.520
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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