STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Experiments
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[Homology]
Score
ADU48607.1Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005: IPR018060: IPR018062; KEGG: ach:Achl_1710 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family. (315 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.725
ADU48606.1
Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059: IPR017909; KEGG: rop:ROP_25030 putative ABC transporter substrate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Putative ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding protein.
 
   
 0.690
ADU46903.1
Putative transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR011663; KEGG: nda:Ndas_2625 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain-containing protein; SPTR: Transcriptional regulator, GntR family; manually curated; PFAM: UTRA domain.
   
  
 0.594
ADU48604.1
Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: mjl:Mjls_4735 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.
 
   
 0.534
ADU48605.1
COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: nda:Ndas_4000 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.
 
   
 0.526
ADU48608.1
InterPro IPR018649; KEGG: tbd:Tbd_2741 hypothetical protein; PFAM: Protein of unknown function DUF2078, membrane; SPTR: Putative uncharacterized protein; PFAM: Predicted membrane protein (DUF2078).
       0.524
ADU48609.1
COGs: COG2132 Putative multicopper oxidase; InterProIPR011707: IPR001117: IPR011706: IPR006311: IPR 002355: IPR017909; KEGG: art:Arth_0198 multicopper oxidase, type 3; PFAM: multicopper oxidase type 3; multicopper oxidase type 1; multicopper oxidase type 2; SPTR: Multicopper oxidase, type 3; PFAM: Multicopper oxidase.
       0.524
ADU49281.1
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR017685; KEGG: xce:Xcel_2242 transcriptional regulator, LysR family; PFAM: regulatory protein LysR; SPTR: Transcriptional regulator, LysR family; TIGRFAM: transcriptional regulator, ArgP family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; TIGRFAM: transcriptional regulator, ArgP family.
   
  
 0.486
ADU47946.1
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: gob:Gobs_0866 silent information regulator protein Sir2; PFAM: Silent information regulator protein Sir2; SPTR: Putative SIR2-like regulatory protein; PFAM: Sir2 family.
  
    0.484
ADU49736.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005; KEGG: sna:Snas_6338 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
  
     0.416
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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