Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU48634.1Zinc uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: mmi:MMAR_3669 zinc uptake regulation protein Zur; PFAM: ferric-uptake regulator; SPTR: Zinc uptake regulation protein Zur; PFAM: Ferric uptake regulator family; Belongs to the Fur family. (134 aa)    
Predicted Functional Partners:
ADU48633.1
ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: gob:Gobs_1600 ABC-3 protein; PFAM: ABC-3 protein; SPTR: Putative metal transport ABC transporter; PFAM: ABC 3 transport family.
 
  
 0.925
ADU48632.1
ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: gob:Gobs_1601 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC-type Mn/Zn transport systems ATPase component; PFAM: ABC transporter.
  
  
 0.919
ADU48631.1
Periplasmic solute binding protein; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006129: IPR006128: IPR006127; KEGG: gob:Gobs_1602 periplasmic solute binding protein; PFAM: periplasmic solute binding protein; SPTR: Putative ABC-transporter metal-binding lipoprotein; PFAM: Periplasmic solute binding protein family; Belongs to the bacterial solute-binding protein 9 family.
 
  
 0.916
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.861
sigA
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.803
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.792
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.767
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.761
ADU48630.1
KEGG: sro:Sros_2344 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.634
ADU46779.1
Transcriptional regulator, GntR family; COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: nfa:nfa49100 putative transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Putative transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family.
  
    0.624
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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