STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48642.1Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: nca:Noca_0392 LysR family transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Transcriptional regulator, LysR family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain. (317 aa)    
Predicted Functional Partners:
ADU47682.1
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: ade:Adeh_2212 LysR family transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Transcriptional regulator, LysR family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain.
  
     0.753
ADU48643.1
Protein of unknown function DUF6 transmembrane; COGs: COG5006 permease DMT superfamily protein; InterPro IPR000620: IPR006311: IPR018073; KEGG: tcu:Tcur_4232 protein of unknown function DUF6 transmembrane; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Putative uncharacterized protein; manually curated; PFAM: EamA-like transporter family.
 
    0.669
ADU50060.1
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: sen:SACE_0264 LysR family transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Probable transcriptional regulator, LysR family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain.
  
     0.587
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
  
 0.586
ADU47107.1
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: sro:Sros_3515 LysR family regulatory protein; PFAM: regulatory protein LysR; LysR substrate-binding; SPTR: LysR family regulatory protein; manually curated; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family.
  
     0.511
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
       0.447
ADU48640.1
KEGG: lme:LEUM_0908 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.441
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.