STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybeYProtein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (155 aa)    
Predicted Functional Partners:
ADU48647.1
PhoH family protein; COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714: IPR008162; KEGG: kra:Krad_3387 PhoH family protein; PFAM: PhoH family protein; SPTR: PhoH-like protein; PFAM: PhoH-like protein.
  
  
 0.983
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
 
  
 0.971
ADU48645.1
COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR002550: IPR000644: IPR005170; KEGG: kse:Ksed_11750 CBS domain-containing protein; PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; SMART: CBS domain containing protein; SPTR: Putative membrane protein; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain.
  
  
 0.875
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
 
 
 
 0.853
ADU47601.1
Rhodanese domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: tfu:Tfu_3085 rhodanese-like protein; PFAM: Rhodanese domain protein; SPTR: Rhodanese-like protein; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain.
  
 
 0.830
ADU49324.1
Rhodanese domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: rha:RHA1_ro11229 hydroxyacylglutathione hydrolase; SMART: Rhodanese domain protein; SPTR: Possible hydroxyacylglutathione hydrolase; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain.
  
 
 0.830
ADU50054.1
Rhodanese domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: nml:Namu_2578 beta-lactamase domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Putative uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain.
  
 
 0.830
ADU48649.1
Histidine triad (HIT) protein; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: nda:Ndas_0706 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: Histidine triad (HIT) protein; PFAM: HIT domain.
   
   0.825
rpsQ
SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
 
 0.813
rplO
LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
 
 
 
 0.812
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.