STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48655.1KEGG: kse:Ksed_11680 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: Protein of unknown function (DUF3097). (296 aa)    
Predicted Functional Partners:
ADU47827.1
Type III restriction protein res subunit; COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR006935: IPR014001: IPR014021; KEGG: kse:Ksed_10520 DNA/RNA helicase, superfamily II; PFAM: type III restriction protein res subunit; SMART: DEAD-like helicase; SPTR: Putative uncharacterized protein; manually curated; PFAM: Type III restriction enzyme, res subunit.
  
     0.759
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
       0.643
ADU48580.1
KEGG: aau:AAur_2439 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3145).
  
     0.635
ADU49747.1
Hypothetical protein; InterPro IPR014487; KEGG: kse:Ksed_05660 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3151).
  
   
 0.594
ADU46567.1
Protein of unknown function DUF721; COGs: COG5512 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives; InterPro IPR007922; KEGG: kra:Krad_0005 protein of unknown function DUF721; PFAM: protein of unknown function DUF721; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF721).
  
     0.569
ADU48652.1
Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
       0.558
dnaJ
Chaperone DnaJ domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...]
       0.558
ADU48461.1
KEGG: sro:Sros_7085 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.543
ADU47878.1
KEGG: jde:Jden_0944 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: DSBA-like thioredoxin domain.
  
     0.472
mca
Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
  
     0.452
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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