STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48655.1KEGG: kse:Ksed_11680 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: Protein of unknown function (DUF3097). (296 aa)    
Predicted Functional Partners:
ADU47827.1
Type III restriction protein res subunit; COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR006935: IPR014001: IPR014021; KEGG: kse:Ksed_10520 DNA/RNA helicase, superfamily II; PFAM: type III restriction protein res subunit; SMART: DEAD-like helicase; SPTR: Putative uncharacterized protein; manually curated; PFAM: Type III restriction enzyme, res subunit.
  
     0.759
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
       0.660
ADU48580.1
KEGG: aau:AAur_2439 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3145).
  
     0.635
ADU49747.1
Hypothetical protein; InterPro IPR014487; KEGG: kse:Ksed_05660 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3151).
  
   
 0.615
dnaJ
Chaperone DnaJ domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...]
       0.580
ADU48652.1
Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
       0.578
ADU46567.1
Protein of unknown function DUF721; COGs: COG5512 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives; InterPro IPR007922; KEGG: kra:Krad_0005 protein of unknown function DUF721; PFAM: protein of unknown function DUF721; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF721).
  
     0.569
ADU48461.1
KEGG: sro:Sros_7085 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.543
ADU47878.1
KEGG: jde:Jden_0944 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: DSBA-like thioredoxin domain.
  
     0.472
ADU48335.1
Protein of unknown function DUF881; COGs: COG3879 conserved hypothetical protein; InterPro IPR010273; KEGG: sco:SCO1387 membrane associated protein; PFAM: protein of unknown function DUF881; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF881).
      
 0.461
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.