STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48672.1Cysteine desulfurase family protein; COGs: COG0520 Selenocysteine lyase; InterPro IPR011340: IPR000192; KEGG: gob:Gobs_4945 cysteine desulfurase family protein; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Putative aminotransferase; TIGRFAM: cysteine desulfurase family protein; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein, VC1184 subfamily. (420 aa)    
Predicted Functional Partners:
ADU48221.1
SUF system FeS assembly protein, NifU family; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871: IPR011341; KEGG: srt:Srot_2325 NifU family SUF system FeS assembly protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family.
 
 
 0.946
ADU48219.1
Iron-regulated ABC transporter ATPase subunit SufC; COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR003593: IPR003439: IPR010230; KEGG: bcv:Bcav_2337 FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: FeS assembly ATPase SufC; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC.
 
  
 0.823
ADU48218.1
Iron-regulated ABC transporter permease protein SufD; COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR000825: IPR011542; KEGG: kse:Ksed_13350 iron-regulated ABC transporter permease protein SufD; PFAM: SufBD protein; SPTR: Putative iron-regulated ABC-type transporter; TIGRFAM: FeS assembly protein SufD; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufD, group 1.
 
 
 0.800
ADU48217.1
Iron-regulated ABC transporter membrane component SufB; COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR000825: IPR010231; KEGG: kra:Krad_2917 FeS assembly protein SufB; PFAM: SufBD protein; SPTR: Putative uncharacterized protein; TIGRFAM: FeS assembly protein SufB; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB.
 
 
 0.791
ADU49066.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR001763: IPR000594: IPR007901; KEGG: ace:Acel_1777 molybdopterin biosynthesis-like protein MoeZ; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; Rhodanese-like domain; ThiF family.
  
 
 0.594
ADU47749.1
COGs: COG2166 SufE protein probably involved in Fe-S center assembly; InterPro IPR003808; KEGG: mlu:Mlut_10710 SufE protein probably involved in Fe-S center assembly; PFAM: Fe-S metabolism associated SufE; SPTR: Fe-S metabolism associated domain protein; PFAM: Fe-S metabolism associated domain.
  
 
 0.579
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
       0.570
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
       0.559
def-2
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
       0.559
ADU48897.1
COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454: IPR000192; KEGG: cai:Caci_1302 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Putative uncharacterized protein; PFAM: Aminotransferase class-V.
  
 
 0.541
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.