STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa)    
Predicted Functional Partners:
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
 
 0.991
asd
Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.978
ADU48960.1
COGs: COG0460 Homoserine dehydrogenase; InterProIPR016204: IPR019811: IPR005106: IPR001342: IPR 002912; KEGG: kra:Krad_1252 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; SPTR: Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain.
 
 
 0.954
ADU47475.1
COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220: IPR020625; KEGG: sro:Sros_2475 putative dihydropicolinate synthase family protein; PFAM: dihydrodipicolinate synthetase; SPTR: Dihydrodipicolinate synthetase; PFAM: Dihydrodipicolinate synthetase family; Belongs to the DapA family.
  
  
 
0.923
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
  
 0.851
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
  
 0.810
ADU46982.1
COGs: COG0527 Aspartokinase; InterProIPR001048: IPR002912: IPR018042: IPR005260: IPR 001341; KEGG: tcu:Tcur_4886 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: Amino acid kinase family; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.
 
  
 0.797
rnj
RNA-metabolising metallo-beta-lactamase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
  
  
 0.698
ADU49112.1
Succinyldiaminopimelate aminotransferase apoenzyme; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR019880: IPR004839: IPR004838; KEGG: tcu:Tcur_1150 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Putative uncharacterized protein; TIGRFAM: succinyldiaminopimelate transaminase; PFAM: Aminotransferase class I and II; TIGRFAM: succinyldiaminopimelate transaminase.
 
  
 0.648
ADU48690.1
Endonuclease/exonuclease/phosphatase; COGs: COG3021 conserved hypothetical protein; InterPro IPR005135; KEGG: sen:SACE_0425 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Putative uncharacterized protein; PFAM: Endonuclease/Exonuclease/phosphatase family.
       0.618
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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