STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48695.1KEGG: avn:Avin_08770 hypothetical protein; SPTR: Putative uncharacterized protein. (371 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.533
ADU48696.1
phenylacetate-CoA oxygenase/reductase, PaaK subunit; COGs: COG1018 Flavodoxin reductase (ferredoxin-NADPH reductase) family 1; InterProIPR011884: IPR006058: IPR001041: IPR017927: IPR 008333: IPR001433: IPR001709: IPR001221; KEGG: kse:Ksed_09330 phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; SPTR: Phenylacetate-CoA oxygenase/reductase, PaaK subunit; TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductas [...]
       0.518
ADU48697.1
phenylacetate-CoA oxygenase, PaaJ subunit; COGs: COG2151 metal-sulfur cluster biosynthetic protein; InterPro IPR011883: IPR002744; KEGG: kse:Ksed_09320 phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; SPTR: Phenylacetate-CoA oxygenase, PaaJ subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; manually curated; PFAM: Domain of unknown function DUF59; TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit.
       0.518
ADU48698.1
phenylacetate-CoA oxygenase, PaaI subunit; COGs: COG3396 conserved hypothetical protein; InterPro IPR011882: IPR007814; KEGG: kse:Ksed_09310 phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; SPTR: Phenylacetate-CoA oxygenase, PaaI subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: Phenylacetic acid catabolic protein; TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit.
       0.518
ADU48699.1
phenylacetate-CoA oxygenase, PaaH subunit; COGs: COG3460 Uncharacterized protein of phenylacetate metabolism; InterPro IPR009359; KEGG: kse:Ksed_09300 phenylacetate-CoA oxygenase, PaaH subunit; PFAM: phenylacetic acid degradation B; SPTR: Phenylacetate-CoA oxygenase, PaaH subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit; PFAM: Phenylacetic acid degradation B; TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit.
       0.470
ADU48700.1
phenylacetate-CoA oxygenase, PaaG subunit; COGs: COG3396 conserved hypothetical protein; InterPro IPR011881: IPR007814; KEGG: kse:Ksed_09290 phenylacetate-CoA oxygenase subunit PaaA; PFAM: phenylacetic acid catabolic family protein; SPTR: Phenylacetate-CoA oxygenase, PaaG subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaG subunit; PFAM: Phenylacetic acid catabolic protein; TIGRFAM: phenylacetate-CoA oxygenase, PaaG subunit.
       0.470
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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