STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48703.1InterPro IPR008407; KEGG: kra:Krad_0205 branched-chain amino acid transport; PFAM: branched-chain amino acid transport; SPTR: Putative uncharacterized protein; PFAM: Branched-chain amino acid transport protein (AzlD). (104 aa)    
Predicted Functional Partners:
ADU48702.1
AzlC family protein; COGs: COG1296 branched-chain amino acid permease (azaleucine resistance); InterPro IPR011606; KEGG: kra:Krad_0206 AzlC family protein; PFAM: AzlC family protein; SPTR: Putative membrane protein; PFAM: AzlC protein.
 
  
 0.989
ADU48701.1
InterPro IPR000182; KEGG: kfl:Kfla_2969 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Putative uncharacterized protein; PFAM: Acetyltransferase (GNAT) family.
 
     0.865
ADU48699.1
phenylacetate-CoA oxygenase, PaaH subunit; COGs: COG3460 Uncharacterized protein of phenylacetate metabolism; InterPro IPR009359; KEGG: kse:Ksed_09300 phenylacetate-CoA oxygenase, PaaH subunit; PFAM: phenylacetic acid degradation B; SPTR: Phenylacetate-CoA oxygenase, PaaH subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit; PFAM: Phenylacetic acid degradation B; TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit.
       0.585
ADU48700.1
phenylacetate-CoA oxygenase, PaaG subunit; COGs: COG3396 conserved hypothetical protein; InterPro IPR011881: IPR007814; KEGG: kse:Ksed_09290 phenylacetate-CoA oxygenase subunit PaaA; PFAM: phenylacetic acid catabolic family protein; SPTR: Phenylacetate-CoA oxygenase, PaaG subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaG subunit; PFAM: Phenylacetic acid catabolic protein; TIGRFAM: phenylacetate-CoA oxygenase, PaaG subunit.
       0.585
ADU48696.1
phenylacetate-CoA oxygenase/reductase, PaaK subunit; COGs: COG1018 Flavodoxin reductase (ferredoxin-NADPH reductase) family 1; InterProIPR011884: IPR006058: IPR001041: IPR017927: IPR 008333: IPR001433: IPR001709: IPR001221; KEGG: kse:Ksed_09330 phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; SPTR: Phenylacetate-CoA oxygenase/reductase, PaaK subunit; TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductas [...]
       0.541
ADU48698.1
phenylacetate-CoA oxygenase, PaaI subunit; COGs: COG3396 conserved hypothetical protein; InterPro IPR011882: IPR007814; KEGG: kse:Ksed_09310 phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; SPTR: Phenylacetate-CoA oxygenase, PaaI subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: Phenylacetic acid catabolic protein; TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit.
       0.537
ADU48697.1
phenylacetate-CoA oxygenase, PaaJ subunit; COGs: COG2151 metal-sulfur cluster biosynthetic protein; InterPro IPR011883: IPR002744; KEGG: kse:Ksed_09320 phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; SPTR: Phenylacetate-CoA oxygenase, PaaJ subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; manually curated; PFAM: Domain of unknown function DUF59; TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit.
       0.536
ADU47291.1
KEGG: gob:Gobs_0955 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.470
ADU49004.1
KEGG: gob:Gobs_4274 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.421
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.408
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.