STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADU48711.1KEGG: mno:Mnod_0253 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: NADH-dependant formate dehydrogenase delta subunit FdsD. (85 aa)    
Predicted Functional Partners:
ADU48710.1
Formate dehydrogenase alpha subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR006478: IPR017900: IPR006655: IPR001041: IPR 017896: IPR019574: IPR006963: IPR006656: IPR006657; KEGG: msm:MSMEG_0161 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; molydopterin dinucleotide-binding region; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; Molydopt [...]
  
 0.993
ADU48708.1
Formate dehydrogenase, gamma subunit; COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; KEGG: msm:MSMEG_0159 formate dehydrogenase, gamma subunit; SPTR: Formate dehydrogenase; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit.
   
 0.986
ADU48709.1
Formate dehydrogenase beta subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR001949: IPR011538: IPR019554: IPR019575; KEGG: msm:MSMEG_0160 formate dehydrogenase, beta subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH oxidoreductase (Quinone), F subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB [...]
   
 0.986
ADU47389.1
Glutathione-independent formaldehyde dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154: IPR013149: IPR014184: IPR002328; KEGG: gob:Gobs_4986 formaldehyde dehydrogenase, glutathione-independent; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: Formaldehyde dehydrogenase, glutathione-independent; TIGRFAM: formaldehyde dehydrogenase, glutathione-independent; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: formaldehyde dehydrogenase, gl [...]
     
 0.903
ADU49350.1
Glutathione-independent formaldehyde dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154: IPR013149: IPR014184: IPR002328; KEGG: gob:Gobs_4986 formaldehyde dehydrogenase, glutathione-independent; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: Formaldehyde dehydrogenase, glutathione-independent; TIGRFAM: formaldehyde dehydrogenase, glutathione-independent; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: formaldehyde dehydrogenase, gl [...]
     
 0.903
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
     
  0.900
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
  0.800
ADU47130.1
Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301: IPR012302: IPR001891; KEGG: nca:Noca_0113 malate dehydrogenase; PFAM: malic protein NAD-binding; malic protein domain protein; SPTR: Malate dehydrogenase (Oxaloacetate-decarboxylating); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain.
     
  0.800
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
     
  0.800
ADU47357.1
COGs: COG2225 Malate synthase; InterPro IPR011076: IPR006252: IPR019830; KEGG: kfl:Kfla_0722 malate synthase A; PFAM: Malate synthase family protein; PRIAM: Malate synthase; SPTR: Malate synthase; TIGRFAM: malate synthase A; PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family.
     
  0.800
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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