Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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ADU48730.1Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR018365: IPR001182; KEGG: fal:FRAAL1920 rod shape-determining membrane protein; cell elongation; PFAM: cell cycle protein; SPTR: Sfr protein; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family. (400 aa)    
Predicted Functional Partners:
ADU48714.1
Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311: IPR001460; KEGG: tbi:Tbis_1685 penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative penicillin-binding protein; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2.
 
 0.941
ADU48032.1
Cell division-specific peptidoglycan biosynthesis regulator FtsW; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437: IPR018365: IPR001182; KEGG: kra:Krad_3200 cell division protein FtsW; PFAM: cell cycle protein; SPTR: Cell division protein FtsW; TIGRFAM: cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family.
  
  
 
0.923
ADU46627.1
Cell elongation-specific peptidoglycan biosynthesis regulator RodA; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: kra:Krad_0074 cell cycle protein; PFAM: cell cycle protein; SPTR: Putative FtsW/RodA/SpoVE family cell cycle protein; PFAM: Cell cycle protein; Belongs to the SEDS family.
  
  
 
0.913
ADU48035.1
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
  
 
 0.901
ADU46626.1
Cell elongation-specific peptidoglycan D,D-transpeptidase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR001460; KEGG: kse:Ksed_00200 cell division protein FtsI/penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: PbpA; PFAM: Penicillin binding protein transpeptidase domain.
 
 0.891
ADU48717.1
Rod shape-determining protein MreB; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: fal:FRAAL1916 rod shape-determining protein MreB; PFAM: cell shape determining protein MreB/Mrl; SPTR: Rod shape-determining protein; TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family.
 
 
 0.846
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.836
ADU48731.1
Riboflavin kinase; COGs: COG0196 FAD synthase; InterPro IPR004821: IPR002606: IPR015864: IPR015865; KEGG: ske:Sked_23420 FMN adenylyltransferase/riboflavin kinase; PFAM: FAD synthetase; Riboflavin kinase; SPTR: Riboflavin kinase/ FMN adenyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; manually curated; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family.
  
  
 0.828
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.814
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.788
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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