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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48745.1Haloacid dehalogenase domain protein hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834: IPR005833; KEGG: nca:Noca_3196 HAD family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Hydrolase; PFAM: haloacid dehalogenase-like hydrolase. (239 aa)    
Predicted Functional Partners:
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
       0.824
ADU48744.1
Protein of unknown function DUF81; COGs: COG0730 permease; InterPro IPR002781; KEGG: nca:Noca_0959 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: Putative uncharacterized protein; PFAM: Sulfite exporter TauE/SafE.
       0.786
ADU48743.1
Ferric reductase domain protein transmembrane component domain; COGs: COG4097 ferric reductase; InterProIPR017927: IPR013130: IPR008333: IPR001433: IPR 001221; KEGG: amd:AMED_3689 oxidoreductase; PFAM: Ferric reductase domain protein transmembrane component domain; Oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; SPTR: Putative oxidoreductase; PFAM: Ferric reductase like transmembrane component; Oxidoreductase NAD-binding domain.
       0.572
ADU48742.1
FMN-binding domain protein; InterPro IPR007329; KEGG: sma:SAV_6771 hypothetical protein; PFAM: FMN-binding domain protein; SPTR: Putative uncharacterized protein; PFAM: FMN-binding domain.
       0.517
ADU48741.1
ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
       0.513
ADU48171.1
Hypothetical protein; InterPro IPR005829; KEGG: saq:Sare_0209 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.463
ADU48747.1
GCN5-related N-acetyltransferase; COGs: COG3393 acetyltransferase; InterPro IPR000182; KEGG: nca:Noca_3472 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: FR47-like protein.
 
     0.462
ADU48175.1
InterPro IPR000421; KEGG: kfl:Kfla_3096 coagulation factor 5/8 type domain protein; PFAM: coagulation factor 5/8 type domain protein; SPTR: Coagulation factor 5/8 type domain protein; PFAM: Domain of unknown function (DUF3367).
  
     0.434
ADU49093.1
KEGG: tcu:Tcur_1191 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.434
ADU48170.1
Polysaccharide biosynthesis protein; InterPro IPR002797; KEGG: tpr:Tpau_0415 xylose transporter; PFAM: polysaccharide biosynthesis protein; SPTR: Putative uncharacterized protein; PFAM: Polysaccharide biosynthesis protein.
 
     0.421
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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