Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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ADU48770.1Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR017200: IPR007197; KEGG: nca:Noca_4381 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily. (400 aa)    
Predicted Functional Partners:
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
 
 0.915
ADU49335.1
Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR006638: IPR017200: IPR007197; KEGG: nca:Noca_1430 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily.
  
  
 
0.908
ADU48417.1
Chlorite dismutase; COGs: COG3253 conserved hypothetical protein; InterPro IPR010644; KEGG: kfl:Kfla_3727 chlorite dismutase; PFAM: Chlorite dismutase; SPTR: Putative uncharacterized protein; PFAM: Chlorite dismutase.
   
 
 0.905
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
     
  0.900
ADU48769.1
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
 
   
 0.830
ADU48768.1
KEGG: kse:Ksed_11250 predicted Rossmann fold nucleotide-binding protein; SPTR: Putative uncharacterized protein; PFAM: Possible lysine decarboxylase.
  
    0.555
ADU47205.1
Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; COGs: COG1587 Uroporphyrinogen-III synthase; InterPro IPR000878: IPR003754: IPR003043; KEGG: kra:Krad_0619 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD.
 
  
 0.525
ADU46853.1
Nitric oxide reductase, NorZ apoprotein; COGs: COG3256 Nitric oxide reductase large subunit; InterPro IPR000883; KEGG: mjl:Mjls_1539 nitric-oxide reductase subunit B; PFAM: cytochrome c oxidase subunit I; SPTR: Nitric oxide reductase; PFAM: Cytochrome C and Quinol oxidase polypeptide I.
 
  
 0.491
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
     
 0.484
ADU49493.1
40-residue YVTN family beta-propeller repeat protein; COGs: COG3391 conserved hypothetical protein; InterPro IPR011964; KEGG: nca:Noca_3772 YVTN beta-propeller repeat-containing protein; SPTR: 40-residue YVTN family beta-propeller repeat protein; TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: 3-carboxy-cis,cis-muconate lactonizing enzyme; TIGRFAM: 40-residue YVTN family beta-propeller repeat.
 
  
 0.461
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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