STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48795.1Signal peptidase I; InterPro IPR000223: IPR019758: IPR019759; KEGG: kra:Krad_1404 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: Putative signal peptidase; TIGRFAM: signal peptidase I; PFAM: Peptidase S26; Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. (307 aa)    
Predicted Functional Partners:
ADU48796.1
Signal peptidase I; InterPro IPR000223: IPR019758: IPR019759; KEGG: kra:Krad_1403 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Signal peptidase I; TIGRFAM: signal peptidase I; manually curated; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.
 
  
 
0.969
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
 
  
 0.926
ADU48793.1
Protein of unknown function DUF2469; InterPro IPR019592; KEGG: sen:SACE_6046 hypothetical protein; PFAM: Protein of unknown function DUF2469; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2469).
       0.796
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.702
ADU50122.1
Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001: IPR000215; KEGG: cfl:Cfla_3727 membrane protein insertase, YidC/Oxa1 family; PFAM: 60 kDa inner membrane insertion protein; SPTR: Putative inner membrane protein translocase component YidC; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain.
 
  
 0.663
ADU50092.1
Peptidoglycan glycosyltransferase; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264: IPR001460; KEGG: kra:Krad_4341 glycosyl transferase family 51; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative secreted penicillin-binding protein; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase.
  
   
 0.612
rplS
LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
  
 0.611
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.577
ADU48792.1
Uncharacterized protein family UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509; KEGG: nca:Noca_3248 hypothetical protein; PFAM: Uncharacterised protein family UPF0102; SPTR: UPF0102 protein Noca_3248; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: conserved hypothetical protein TIGR00252.
  
    0.563
glyQ
COGs: COG0751 Glycyl-tRNA synthetase beta subunit; InterPro IPR006194: IPR002310: IPR002311: IPR015944; KEGG: kfl:Kfla_5824 glycyl-tRNA synthetase, beta subunit; PFAM: glycyl-tRNA synthetase alpha subunit; glycyl-tRNA synthetase beta subunit; PRIAM: Glycine--tRNA ligase; SPTR: Glycyl-tRNA synthetase, beta subunit; TIGRFAM: glycyl-tRNA synthetase, beta subunit; glycyl-tRNA synthetase, alpha subunit; PFAM: Glycyl-tRNA synthetase beta subunit; Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, beta subunit; glycyl-tRNA synthetase, tetrameric type, alph [...]
     
 0.543
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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