STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48804.1Amidohydrolase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: sma:SAV_6403 hypothetical protein; PFAM: amidohydrolase; SPTR: Putative uncharacterized protein; PFAM: Amidohydrolase family. (362 aa)    
Predicted Functional Partners:
ADU48803.1
Hypothetical protein; COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; KEGG: kse:Ksed_11030 acetyltransferase, ribosomal protein N-acetylase; SPTR: Acetyltransferase, ribosomal protein N-acetylase.
       0.795
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
  
  
 0.786
ADU49823.1
COGs: COG2986 Histidine ammonia-lyase; InterPro IPR001106: IPR005921; KEGG: nfa:nfa12280 histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; PRIAM: Histidine ammonia-lyase; SPTR: Histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: Phenylalanine and histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase.
  
  
 0.785
ffh
Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
       0.628
ADU48492.1
Response regulator receiver; InterPro IPR001789; KEGG: bcv:Bcav_1893 response regulator receiver protein; SMART: response regulator receiver; SPTR: Putative two-component system response regulator; PFAM: Response regulator receiver domain.
  
     0.534
ADU48801.1
COGs: COG1837 RNA-binding protein (contains KH domain); InterPro IPR020627: IPR004088; KEGG: jde:Jden_0986 KH domain protein; SPTR: Putative uncharacterized protein; Belongs to the UPF0109 family.
       0.511
rpsP
COGs: COG0228 Ribosomal protein S16; InterPro IPR000307: IPR020592; KEGG: kse:Ksed_11040 SSU ribosomal protein S16P; PFAM: ribosomal protein S16; SPTR: 30s ribosomal protein s16; TIGRFAM: ribosomal protein S16; PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
       0.511
ADU46729.1
KEGG: kse:Ksed_01600 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.472
glnD
UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
       0.416
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.