STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48826.1DAK2 domain fusion protein YloV; COGs: COG1461 kinase related to dihydroxyacetone kinase; InterPro IPR019986: IPR004007; KEGG: sgr:SGR_1915 putative dihydroxyacetone kinase; PFAM: Dak phosphatase; SPTR: Putative dihydroxyacetone kinase; TIGRFAM: DAK2 domain fusion protein YloV; PFAM: DAK2 domain; TIGRFAM: DAK2 domain fusion protein YloV. (588 aa)    
Predicted Functional Partners:
ADU47938.1
degV family protein; COGs: COG1307 conserved hypothetical protein; InterPro IPR003797; KEGG: sco:SCO2569 hypothetical protein; PFAM: DegV family protein; SPTR: Putative uncharacterized protein; TIGRFAM: degV family protein; PFAM: Uncharacterised protein, DegV family COG1307; TIGRFAM: EDD domain protein, DegV family.
 
 0.987
ADU48825.1
COGs: COG1200 RecG-like helicase; InterProIPR014001: IPR001650: IPR014021: IPR004365: IPR 011545; KEGG: tfu:Tfu_0646 ATP-dependent DNA helicase RecG; PFAM: DEAD/DEAH box helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Putative ATP-dependent DNA helicase; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecG.
  
    0.920
ADU48824.1
Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398: IPR002052; KEGG: nda:Ndas_0208 methyltransferase; PFAM: Conserved hypothetical protein CHP00095; SPTR: Methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family.
 
     0.862
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
     0.861
rnc
RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
    0.655
rpmF
LSU ribosomal protein L32P; InterPro IPR002677; KEGG: cfl:Cfla_2294 ribosomal protein L32; PFAM: ribosomal L32p protein; SPTR: 50S ribosomal protein L32; TIGRFAM: ribosomal protein L32; PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
       0.646
ADU48822.1
Protein of unknown function DUF177; COGs: COG1399 metal-binding possibly nucleic acid-binding protein; InterPro IPR003772; KEGG: cfl:Cfla_2295 protein of unknown function DUF177; PFAM: protein of unknown function DUF177; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1399.
       0.646
mutM
DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
    0.586
ADU48827.1
Aminoglycoside phosphotransferase; COGs: COG3001 conserved hypothetical protein; InterPro IPR016477: IPR002575; KEGG: cmi:CMM_1084 putative sugar kinase; PFAM: aminoglycoside phosphotransferase; SPTR: Putative uncharacterized protein; PFAM: Fructosamine kinase.
       0.559
rpmB
COGs: COG0227 Ribosomal protein L28; InterPro IPR001383; KEGG: scb:SCAB_26481 putative 50S ribosomal protein L28; PFAM: ribosomal protein L28; SPTR: 50S ribosomal protein L28; TIGRFAM: ribosomal protein L28; PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
     
 0.529
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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