Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU48850.1Regulatory protein TetR; InterPro IPR001647: IPR003012; KEGG: cmi:CMM_1624 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: Putative transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family. (192 aa)    
Predicted Functional Partners:
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
 
   
 0.698
ADU48852.1
COGs: COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; InterPro IPR005815: IPR005814; KEGG: rsa:RSal33209_0558 sdenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; SPTR: Sdenosylmethionine-8-amino-7-oxononanoate aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.600
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
       0.558
ADU47932.1
BioY protein; COGs: COG1268 conserved hypothetical protein; InterPro IPR003784; KEGG: gob:Gobs_1529 BioY protein; PFAM: BioY protein; SPTR: Uncharacterized conserved protein-like protein; PFAM: BioY family.
 
   
 0.436
ADU47931.1
COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: nml:Namu_4656 cobalt transport protein; PFAM: cobalt transport protein; SPTR: Putative uncharacterized protein; PFAM: Cobalt transport protein.
 
   
 0.402
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.