Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU48860.1Amino acid/polyamine/organocation transporter, APC superfamily; COGs: COG0531 Amino acid transporter; InterPro IPR002293: IPR004841; KEGG: ace:Acel_1853 amino acid permease-associated region; PFAM: amino acid permease-associated region; SPTR: Amino acid permease-associated region; PFAM: Amino acid permease; TIGRFAM: amino acid permease (GABA permease); TC 2.A.3. (520 aa)    
Predicted Functional Partners:
ADU48858.1
COGs: COG0174 Glutamine synthetase; InterPro IPR008146; KEGG: ace:Acel_1851 L-glutamine synthetase; PFAM: glutamine synthetase catalytic region; PRIAM: Glutamate--ammonia ligase; SPTR: Putative glutamine synthetase; PFAM: Glutamine synthetase, catalytic domain.
 
   
 0.871
ADU48859.1
Transcriptional regulator, GntR family; COGs: COG2186 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: ace:Acel_1852 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Putative transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
 
   
 0.842
ADU48856.1
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198: IPR002347; KEGG: nca:Noca_2585 short chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short chain dehydrogenase; PFAM: short chain dehydrogenase.
 
 
 
 0.722
ADU48855.1
Peptidase C26; COGs: COG2071 glutamine amidotransferase; InterPro IPR017926: IPR011697; KEGG: ace:Acel_1848 peptidase C26; PFAM: peptidase C26; SPTR: Putative uncharacterized protein; PFAM: Peptidase C26.
 
  
 0.675
ADU48857.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR015590; KEGG: amd:AMED_1809 phenylacetaldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Probable aldehyde dehydrogenase AldC; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
 
  
 0.587
ADU48862.1
COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786: IPR018300: IPR001544; KEGG: nca:Noca_3367 branched chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched-chain-amino-acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II.
  
  
 0.564
ADU48861.1
COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR000150: IPR006379: IPR013200; KEGG: ske:Sked_07610 HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: HAD-superfamily hydrolase, subfamily IIB; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB.
   
   0.555
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
  
 0.501
ADU46725.1
Sodium:neurotransmitter symporter; COGs: COG0733 Na+-dependent transporter of the SNF family; InterPro IPR000175; KEGG: cfl:Cfla_0709 sodium:neurotransmitter symporter; PFAM: sodium:neurotransmitter symporter; SPTR: Transporter; PFAM: Sodium:neurotransmitter symporter family; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
  
 
 0.488
ADU49215.1
Alpha-1,6-glucosidase, pullulanase-type; COGs: COG1523 Type II secretory pathway pullulanase PulA and related glycosidase; InterPro IPR006589: IPR011839: IPR006047: IPR004193; KEGG: kfl:Kfla_2775 alpha-1,6-glucosidase, pullulanase-type; PFAM: alpha amylase catalytic region; glycoside hydrolase family 13 domain protein; SMART: alpha amylase catalytic sub domain; SPTR: Alpha-1,6-glucosidase, pullulanase-type; TIGRFAM: alpha-1,6-glucosidase, pullulanase-type; PFAM: Domain of unknown function (DUF3372); Alpha amylase, catalytic domain; Carbohydrate-binding module 48 (Isoamylase N-terminal [...]
  
 0.469
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.