STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48861.1COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR000150: IPR006379: IPR013200; KEGG: ske:Sked_07610 HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: HAD-superfamily hydrolase, subfamily IIB; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB. (269 aa)    
Predicted Functional Partners:
ADU48862.1
COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786: IPR018300: IPR001544; KEGG: nca:Noca_3367 branched chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched-chain-amino-acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II.
       0.803
ADU48860.1
Amino acid/polyamine/organocation transporter, APC superfamily; COGs: COG0531 Amino acid transporter; InterPro IPR002293: IPR004841; KEGG: ace:Acel_1853 amino acid permease-associated region; PFAM: amino acid permease-associated region; SPTR: Amino acid permease-associated region; PFAM: Amino acid permease; TIGRFAM: amino acid permease (GABA permease); TC 2.A.3.
  
    0.539
ADU48859.1
Transcriptional regulator, GntR family; COGs: COG2186 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: ace:Acel_1852 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Putative transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
  
    0.536
ADU48858.1
COGs: COG0174 Glutamine synthetase; InterPro IPR008146; KEGG: ace:Acel_1851 L-glutamine synthetase; PFAM: glutamine synthetase catalytic region; PRIAM: Glutamate--ammonia ligase; SPTR: Putative glutamine synthetase; PFAM: Glutamine synthetase, catalytic domain.
     
 0.509
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
       0.478
ADU46754.1
HAD-superfamily hydrolase, subfamily IIB; COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200: IPR006379: IPR000150; KEGG: cfl:Cfla_3183 HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: Hydrolase (HAD superfamily protein); TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB.
 
    
0.436
ADU47781.1
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR000644: IPR005835; KEGG: mag:amb0085 nucleoside-diphosphate-sugar pyrophosphorylase; PFAM: Nucleotidyl transferase; CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Nucleoside-diphosphate-sugar pyrophosphorylase; PFAM: Nucleotidyl transferase; CBS domain.
  
  
 0.418
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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