STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48867.1KEGG: sro:Sros_3434 major facilitator transporter; SPTR: Major facilitator transporter. (198 aa)    
Predicted Functional Partners:
ADU48866.1
Protein of unknown function DUF461; COGs: COG2847 conserved hypothetical protein; InterPro IPR007410; KEGG: bfa:Bfae_31000 hypothetical protein; PFAM: protein of unknown function DUF461; SPTR: Uncharacterized conserved protein; PFAM: Protein of unknown function (DUF461).
       0.634
ADU48865.1
Dyp-type peroxidase family; COGs: COG2837 iron-dependent peroxidase; InterPro IPR006314: IPR017909; KEGG: svi:Svir_39250 Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; SPTR: Dyp-type peroxidase family; TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase family; TIGRFAM: Tat-translocated enzyme; Dyp-type peroxidase family.
       0.632
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.460
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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