Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU48910.1Phosphoglucomutase, alpha-D-glucose phosphate-specific; COGs: COG0033 Phosphoglucomutase; InterProIPR005852: IPR016066: IPR005844: IPR005845: IPR 005846: IPR005843; KEGG: nca:Noca_4438 phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: Phosphoglucomutase; TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/be [...] (548 aa)    
Predicted Functional Partners:
ADU48905.1
COGs: COG0058 Glucan phosphorylase; InterPro IPR011834: IPR000811; KEGG: kra:Krad_1298 alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; PRIAM: Phosphorylase; SPTR: Phosphorylase; TIGRFAM: alpha-glucan phosphorylase; manually curated; PFAM: Carbohydrate phosphorylase; Protein of unknown function (DUF3417); TIGRFAM: alpha-glucan phosphorylases.
  
 
 0.991
ADU48205.1
COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672; KEGG: ach:Achl_1836 phosphoglucose isomerase (PGI); PFAM: phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
  
 0.987
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
  
 0.960
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
  
 0.950
ADU47418.1
Molybdenum cofactor synthesis domain protein; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterProIPR002618: IPR005110: IPR001453: IPR005111: IPR 020817; KEGG: kfl:Kfla_5768 UTP--glucose-1-phosphate uridylyltransferase; PFAM: UTP--glucose-1-phosphate uridylyltransferase; MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; PRIAM: UTP--glucose-1-phosphate uridylyltransferase; SPTR: UTP--glucose-1-phosphate uridylyltransferase; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-termi [...]
   
 0.941
ADU48207.1
Transketolase; COGs: COG0021 Transketolase; InterProIPR005474: IPR020826: IPR005475: IPR005476: IPR 005478; KEGG: sgr:SGR_4907 transketolase; PFAM: Transketolase domain-containing protein; Transketolase central region; SPTR: Putative transketolase; TIGRFAM: transketolase; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; Belongs to the transketolase family.
  
 
 0.941
ADU49681.1
COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR003385; KEGG: rca:Rcas_2645 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77; PRIAM: 4-alpha-glucanotransferase; SPTR: 4-alpha-glucanotransferase; PFAM: 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase.
  
 
 0.940
ADU48240.1
Glycogen synthase (ADP-glucose); COGs: COG0438 Glycosyltransferase; InterPro IPR001296: IPR011875; KEGG: kra:Krad_2900 glycogen synthase; PFAM: glycosyl transferase group 1; SPTR: Possible glycosyltransferase; TIGRFAM: glycogen synthase; PFAM: Glycosyl transferases group 1; TIGRFAM: glycogen synthase, Corynebacterium family.
  
 0.928
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 0.922
ADU48908.1
Aminoglycoside phosphotransferase; COGs: COG3281 Uncharacterized protein probably involved in trehalose biosynthesis; InterPro IPR002575; KEGG: bcv:Bcav_1335 aminoglycoside phosphotransferase; PFAM: aminoglycoside phosphotransferase; SPTR: Putative uncharacterized protein.
    
 0.921
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (16%) [HD]