STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADU48939.1FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027; KEGG: fal:FRAAL1622 NADH dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: NADH dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase. (470 aa)    
Predicted Functional Partners:
gpmA
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
   0.769
acpP
Phosphopantetheine-binding protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
   
   0.701
atpD
ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
  
  
 0.602
ADU46777.1
COGs: COG1294 Cytochrome bd-type quinol oxidase subunit 2; InterPro IPR003317; KEGG: nca:Noca_0943 cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; SPTR: Cytochrome d ubiquinol oxidase, subunit II; TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: Cytochrome oxidase subunit II; TIGRFAM: cytochrome d oxidase, subunit II (cydB).
 
   
 0.566
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.563
atpG
ATP synthase F1 subcomplex gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
  
  
 0.543
ADU48236.1
Enoyl-(acyl-carrier-protein) reductase (NADH); COGs: COG0623 Enoyl-(acyl-carrier-protein); InterPro IPR002198; KEGG: cfl:Cfla_1687 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Enoyl-(Acyl carrier protein) reductase; PFAM: short chain dehydrogenase.
      
 0.530
ADU49899.1
COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR006076: IPR000447; KEGG: sen:SACE_6515 glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: Glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
   
 
 0.520
nuoA
NADH dehydrogenase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.
   
  
 0.515
ADU47507.1
COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR006076: IPR000447; KEGG: tpr:Tpau_1956 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
   
 
 0.513
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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