STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48951.1COGs: COG0009 Putative translation factor (SUA5); InterPro IPR004388: IPR006070; KEGG: kra:Krad_1260 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: Sua5/YciO/YrdC/YwlC; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family. (255 aa)    
Predicted Functional Partners:
prmC
protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
 
  
 0.927
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.762
tsaD
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
 
 0.673
ADU48949.1
Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018480: IPR018481; KEGG: kse:Ksed_18290 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; PFAM: Glycosyl transferase family 4.
       0.606
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
  
    0.578
prfA
Bacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
     
 0.568
ADU48952.1
TRAP transporter solute receptor, TAXI family; COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852; KEGG: amd:AMED_2173 TRAP transport system solute receptor; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family.
  
    0.548
ADU49425.1
Histidine kinase; COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003661: IPR003594: IPR005467: IPR004358; KEGG: ach:Achl_0849 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Putative two-component system sensor kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
     0.535
ADU48953.1
TRAP transporter, 4TM/12TM fusion protein; COGs: COG4666 TRAP-type uncharacterized transport system fused permease components; InterPro IPR011853: IPR010656; KEGG: ami:Amir_6905 TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP transporter, 4TM/12TM fusion protein; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein.
       0.528
rpmE
LSU ribosomal protein L31P; Binds the 23S rRNA.
     
 0.493
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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