| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADU46751.1 | ADU48952.1 | Intca_0193 | Intca_2445 | KEGG: ami:Amir_2064 superoxide dismutase; SPTR: Superoxide dismutase; manually curated. | TRAP transporter solute receptor, TAXI family; COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852; KEGG: amd:AMED_2173 TRAP transport system solute receptor; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family. | 0.419 |
| ADU46751.1 | ADU48953.1 | Intca_0193 | Intca_2446 | KEGG: ami:Amir_2064 superoxide dismutase; SPTR: Superoxide dismutase; manually curated. | TRAP transporter, 4TM/12TM fusion protein; COGs: COG4666 TRAP-type uncharacterized transport system fused permease components; InterPro IPR011853: IPR010656; KEGG: ami:Amir_6905 TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP transporter, 4TM/12TM fusion protein; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein. | 0.541 |
| ADU47031.1 | ADU47033.1 | Intca_0484 | Intca_0486 | Protein of unknown function DUF112 transmembrane; COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: ach:Achl_0594 protein of unknown function DUF112 transmembrane; PFAM: protein of unknown function DUF112 transmembrane; SPTR: Putative integral membrane protein; PFAM: Tripartite tricarboxylate transporter TctA family. | COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: art:Arth_1395 hypothetical protein; SPTR: Putative secreted protein; PFAM: Tripartite tricarboxylate transporter family receptor. | 0.993 |
| ADU47031.1 | ADU48952.1 | Intca_0484 | Intca_2445 | Protein of unknown function DUF112 transmembrane; COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: ach:Achl_0594 protein of unknown function DUF112 transmembrane; PFAM: protein of unknown function DUF112 transmembrane; SPTR: Putative integral membrane protein; PFAM: Tripartite tricarboxylate transporter TctA family. | TRAP transporter solute receptor, TAXI family; COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852; KEGG: amd:AMED_2173 TRAP transport system solute receptor; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family. | 0.436 |
| ADU47031.1 | ADU48953.1 | Intca_0484 | Intca_2446 | Protein of unknown function DUF112 transmembrane; COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: ach:Achl_0594 protein of unknown function DUF112 transmembrane; PFAM: protein of unknown function DUF112 transmembrane; SPTR: Putative integral membrane protein; PFAM: Tripartite tricarboxylate transporter TctA family. | TRAP transporter, 4TM/12TM fusion protein; COGs: COG4666 TRAP-type uncharacterized transport system fused permease components; InterPro IPR011853: IPR010656; KEGG: ami:Amir_6905 TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP transporter, 4TM/12TM fusion protein; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein. | 0.530 |
| ADU47033.1 | ADU47031.1 | Intca_0486 | Intca_0484 | COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: art:Arth_1395 hypothetical protein; SPTR: Putative secreted protein; PFAM: Tripartite tricarboxylate transporter family receptor. | Protein of unknown function DUF112 transmembrane; COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: ach:Achl_0594 protein of unknown function DUF112 transmembrane; PFAM: protein of unknown function DUF112 transmembrane; SPTR: Putative integral membrane protein; PFAM: Tripartite tricarboxylate transporter TctA family. | 0.993 |
| ADU47033.1 | ADU48952.1 | Intca_0486 | Intca_2445 | COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: art:Arth_1395 hypothetical protein; SPTR: Putative secreted protein; PFAM: Tripartite tricarboxylate transporter family receptor. | TRAP transporter solute receptor, TAXI family; COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852; KEGG: amd:AMED_2173 TRAP transport system solute receptor; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family. | 0.449 |
| ADU47033.1 | ADU48953.1 | Intca_0486 | Intca_2446 | COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: art:Arth_1395 hypothetical protein; SPTR: Putative secreted protein; PFAM: Tripartite tricarboxylate transporter family receptor. | TRAP transporter, 4TM/12TM fusion protein; COGs: COG4666 TRAP-type uncharacterized transport system fused permease components; InterPro IPR011853: IPR010656; KEGG: ami:Amir_6905 TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP transporter, 4TM/12TM fusion protein; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein. | 0.480 |
| ADU48951.1 | ADU48952.1 | Intca_2444 | Intca_2445 | COGs: COG0009 Putative translation factor (SUA5); InterPro IPR004388: IPR006070; KEGG: kra:Krad_1260 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: Sua5/YciO/YrdC/YwlC; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family. | TRAP transporter solute receptor, TAXI family; COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852; KEGG: amd:AMED_2173 TRAP transport system solute receptor; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family. | 0.548 |
| ADU48951.1 | ADU48953.1 | Intca_2444 | Intca_2446 | COGs: COG0009 Putative translation factor (SUA5); InterPro IPR004388: IPR006070; KEGG: kra:Krad_1260 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: Sua5/YciO/YrdC/YwlC; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family. | TRAP transporter, 4TM/12TM fusion protein; COGs: COG4666 TRAP-type uncharacterized transport system fused permease components; InterPro IPR011853: IPR010656; KEGG: ami:Amir_6905 TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP transporter, 4TM/12TM fusion protein; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein. | 0.528 |
| ADU48951.1 | glyA | Intca_2444 | Intca_2443 | COGs: COG0009 Putative translation factor (SUA5); InterPro IPR004388: IPR006070; KEGG: kra:Krad_1260 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: Sua5/YciO/YrdC/YwlC; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.762 |
| ADU48951.1 | prfA | Intca_2444 | Intca_2448 | COGs: COG0009 Putative translation factor (SUA5); InterPro IPR004388: IPR006070; KEGG: kra:Krad_1260 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: Sua5/YciO/YrdC/YwlC; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family. | Bacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.568 |
| ADU48951.1 | prmC | Intca_2444 | Intca_2447 | COGs: COG0009 Putative translation factor (SUA5); InterPro IPR004388: IPR006070; KEGG: kra:Krad_1260 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: Sua5/YciO/YrdC/YwlC; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family. | protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.927 |
| ADU48952.1 | ADU46751.1 | Intca_2445 | Intca_0193 | TRAP transporter solute receptor, TAXI family; COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852; KEGG: amd:AMED_2173 TRAP transport system solute receptor; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family. | KEGG: ami:Amir_2064 superoxide dismutase; SPTR: Superoxide dismutase; manually curated. | 0.419 |
| ADU48952.1 | ADU47031.1 | Intca_2445 | Intca_0484 | TRAP transporter solute receptor, TAXI family; COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852; KEGG: amd:AMED_2173 TRAP transport system solute receptor; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family. | Protein of unknown function DUF112 transmembrane; COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: ach:Achl_0594 protein of unknown function DUF112 transmembrane; PFAM: protein of unknown function DUF112 transmembrane; SPTR: Putative integral membrane protein; PFAM: Tripartite tricarboxylate transporter TctA family. | 0.436 |
| ADU48952.1 | ADU47033.1 | Intca_2445 | Intca_0486 | TRAP transporter solute receptor, TAXI family; COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852; KEGG: amd:AMED_2173 TRAP transport system solute receptor; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family. | COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: art:Arth_1395 hypothetical protein; SPTR: Putative secreted protein; PFAM: Tripartite tricarboxylate transporter family receptor. | 0.449 |
| ADU48952.1 | ADU48951.1 | Intca_2445 | Intca_2444 | TRAP transporter solute receptor, TAXI family; COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852; KEGG: amd:AMED_2173 TRAP transport system solute receptor; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family. | COGs: COG0009 Putative translation factor (SUA5); InterPro IPR004388: IPR006070; KEGG: kra:Krad_1260 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: Sua5/YciO/YrdC/YwlC; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family. | 0.548 |
| ADU48952.1 | ADU48953.1 | Intca_2445 | Intca_2446 | TRAP transporter solute receptor, TAXI family; COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852; KEGG: amd:AMED_2173 TRAP transport system solute receptor; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family. | TRAP transporter, 4TM/12TM fusion protein; COGs: COG4666 TRAP-type uncharacterized transport system fused permease components; InterPro IPR011853: IPR010656; KEGG: ami:Amir_6905 TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP transporter, 4TM/12TM fusion protein; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein. | 0.997 |
| ADU48952.1 | ADU49458.1 | Intca_2445 | Intca_2963 | TRAP transporter solute receptor, TAXI family; COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852; KEGG: amd:AMED_2173 TRAP transport system solute receptor; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family. | KEGG: saq:Sare_3570 excisionase/Xis, DNA-binding; SPTR: Excisionase/Xis, DNA-binding; TIGRFAM: DNA binding domain, excisionase family. | 0.424 |
| ADU48952.1 | glyA | Intca_2445 | Intca_2443 | TRAP transporter solute receptor, TAXI family; COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852; KEGG: amd:AMED_2173 TRAP transport system solute receptor; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.429 |