STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prfABacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (359 aa)    
Predicted Functional Partners:
prmC
protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
 
 
 0.997
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
 
 0.978
rplT
LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
 
 
 0.973
rpmA
COGs: COG0211 Ribosomal protein L27; InterPro IPR001684: IPR018261; KEGG: srt:Srot_1753 50S ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: Ribosomal protein L27; TIGRFAM: ribosomal protein L27; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
 
 
 0.971
rpsG
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.969
rpmE
LSU ribosomal protein L31P; Binds the 23S rRNA.
  
 
 0.963
ADU47079.1
Methyltransferase small; COGs: COG2890 Methylase of polypeptide chain release factors; InterPro IPR007848: IPR002052; KEGG: kse:Ksed_25140 methyltransferase family protein; PFAM: methyltransferase small; SPTR: Putative transferase; PFAM: Methyltransferase small domain; TIGRFAM: HemK family putative methylases; Belongs to the methyltransferase superfamily.
  
 
 0.960
rpsI
COGs: COG0103 Ribosomal protein S9; InterPro IPR000754: IPR020574; KEGG: krh:KRH_06470 30S ribosomal protein S9; PFAM: ribosomal protein S9; SPTR: 30S ribosomal protein S9; PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family.
 
 
 0.960
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
 
 
 0.958
rplC
LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
 
 0.953
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.