STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU48969.1Carbohydrate kinase, FGGY; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484: IPR018485: IPR018483; KEGG: kse:Ksed_11390 pentulose/hexulose kinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Pentulose/hexulose kinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: gluconate kinase, FGGY type; Belongs to the FGGY kinase family. (541 aa)    
Predicted Functional Partners:
ADU48976.1
6-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
 
  
 0.940
ADU46565.1
COGs: COG1023 6-phosphogluconate dehydrogenase; InterPro IPR006115: IPR006114: IPR004849: IPR006183; KEGG: kse:Ksed_00030 6-phosphogluconate dehydrogenase (decarboxylating); PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain-containing protein; SPTR: 6-phosphogluconate dehydrogenase, decarboxylating; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; manually curated; PFAM: 6-phosphogluconate dehydrogenase, C-terminal domain; NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 6-phosphogluconate dehydrogenase (decarboxylating).
 
 
 0.938
ADU48049.1
Gluconate kinase, SKI family; COGs: COG3265 Gluconate kinase; InterPro IPR006001: IPR000623; KEGG: art:Arth_0505 gluconate kinase; PFAM: shikimate kinase; PRIAM: Gluconokinase; SPTR: Gluconate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: Shikimate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family.
     
 0.926
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
   
 0.919
uxaC
COGs: COG1904 Glucuronate isomerase; InterPro IPR003766; KEGG: fre:Franean1_3197 glucuronate isomerase; PFAM: Glucuronate isomerase; PRIAM: Glucuronate isomerase; SPTR: Glucuronate isomerase; PFAM: Glucuronate isomerase.
 
   
 0.836
ADU48970.1
COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR000669: IPR013131: IPR013118; KEGG: fre:Franean1_3198 mannitol dehydrogenase domain-containing protein; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; SPTR: Mannitol dehydrogenase domain protein; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain.
 
  
 0.827
ADU47645.1
COGs: COG2610 H+/gluconate symporter and related permease; InterPro IPR003474; KEGG: spe:Spro_1488 inner membrane permease YgbN; PFAM: Gluconate transporter; SPTR: Gluconate transporter; TIGRFAM: gluconate transporter; PFAM: GntP family permease; TIGRFAM: gluconate transporter.
 
  
 0.681
ADU49743.1
PTS system D-fructose-specific IIABC components (F1P-forming), Frc family; COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR002178: IPR013011: IPR013014: IPR004715: IPR 003353: IPR006327: IPR003352; KEGG: sco:SCO3196 fructose-specific permease; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: Fructose-specific permease; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: Phosphotransferase s [...]
     
 0.618
ADU48972.1
Protein of unknown function DUF2088; COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: fre:Franean1_3196 hypothetical protein; PFAM: Protein of unknown function DUF2088; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088).
       0.545
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 
 0.482
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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