STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU48973.1Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: fre:Franean1_3256 LacI family transcription regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family. (357 aa)    
Predicted Functional Partners:
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
    
 
 0.865
uxaC
COGs: COG1904 Glucuronate isomerase; InterPro IPR003766; KEGG: fre:Franean1_3197 glucuronate isomerase; PFAM: Glucuronate isomerase; PRIAM: Glucuronate isomerase; SPTR: Glucuronate isomerase; PFAM: Glucuronate isomerase.
 
  
 0.730
ADU49653.1
Inner-membrane translocator; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: nca:Noca_0101 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component.
 
  
 0.618
ADU49742.1
COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR001020: IPR000032: IPR005698; KEGG: cmi:CMM_1505 phosphotransferase system, phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; SPTR: Phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
 
 
 
 0.614
ADU49743.1
PTS system D-fructose-specific IIABC components (F1P-forming), Frc family; COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR002178: IPR013011: IPR013014: IPR004715: IPR 003353: IPR006327: IPR003352; KEGG: sco:SCO3196 fructose-specific permease; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: Fructose-specific permease; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: Phosphotransferase s [...]
     
 0.579
ADU48974.1
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: fre:Franean1_3256 LacI family transcription regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family.
 
    
0.567
ADU48970.1
COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR000669: IPR013131: IPR013118; KEGG: fre:Franean1_3198 mannitol dehydrogenase domain-containing protein; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; SPTR: Mannitol dehydrogenase domain protein; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain.
 
  
 0.548
ADU48972.1
Protein of unknown function DUF2088; COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: fre:Franean1_3196 hypothetical protein; PFAM: Protein of unknown function DUF2088; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088).
  
     0.514
ADU49654.1
ABC transporter related protein; COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: nca:Noca_0100 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter ATP binding protein; PFAM: ABC transporter.
 
  
 0.452
rbsK
PfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.425
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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