STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
whiB-4Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (82 aa)    
Predicted Functional Partners:
sigA
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.846
ADU47826.1
KEGG: aau:AAur_2578 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3039).
  
     0.768
ADU48328.1
Regulatory protein MerR; InterPro IPR000551; KEGG: aau:AAur_1684 hypothetical protein; SMART: regulatory protein MerR; SPTR: Putative uncharacterized protein.
  
     0.768
ADU48793.1
Protein of unknown function DUF2469; InterPro IPR019592; KEGG: sen:SACE_6046 hypothetical protein; PFAM: Protein of unknown function DUF2469; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2469).
  
     0.767
nucS
Protein of unknown function DUF91; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.736
ADU48200.1
Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
     0.735
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.732
ADU50104.1
Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterProIPR002646: IPR006674: IPR014065: IPR006675: IPR 003607; KEGG: kse:Ksed_26890 tRNA adenylyltransferase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Putative RNA nucleotidyltransferase; TIGRFAM: tRNA adenylyltransferase; metal dependent phophohydrolase; PFAM: HD domain; Poly A polymerase head domain; TIGRFAM: tRNA adenylyltransferase; uncharac [...]
  
     0.677
ADU46573.1
KEGG: kra:Krad_0008 hypothetical protein; SPTR: Putative integral membrane protein; PFAM: Transmembrane domain of unknown function (DUF3566).
  
     0.671
ADU47877.1
Membrane alanyl aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR012778: IPR014782: IPR005829; KEGG: kse:Ksed_09020 aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; PRIAM: Membrane alanyl aminopeptidase; SPTR: Aminopeptidase N; TIGRFAM: aminopeptidase N; PFAM: Domain of unknown function (DUF3358); Peptidase family M1; TIGRFAM: aminopeptidase N, Streptomyces lividans type.
  
     0.654
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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